Anti-inflammatory effect of biologic therapy in patients with psoriatic disease: A prospective cohort FDG PET study

• Published in: Journal of nuclear cardiology Vol. 30; no. 4; pp. 1642 - 1652
• Main Authors: Boczar, Kevin E., Beanlands, Rob S., Glassman, Steven J., Wang, Jerry, Zeng, Wanzhen, deKemp, Robert A., Ward, Natalie C., Fehlmann, Christophe A., Wells, George A., Karsh, Jacob, Dwivedi, Girish
• Format: Journal Article
• Language: English
• Published: Cham Elsevier Inc 01.08.2023; Springer International Publishing; Springer Nature B.V
• Subjects: Anti-Inflammatory Agents - therapeutic use; Arthritis, Psoriatic - diagnostic imaging; Arthritis, Psoriatic - drug therapy; Biological Factors - therapeutic use; Cardiology; cardiovascular disease; Coronary vessels; Fluorodeoxyglucose F18 - therapeutic use; Humans; Imaging; inflammation; Inflammation - diagnostic imaging; Medicine; Medicine & Public Health; Nuclear Medicine; Original; Original Article; PET imaging; Positron-Emission Tomography; Prospective Studies; Psoriasis; Psoriasis - diagnostic imaging; Psoriasis - drug therapy; Psoriatic arthritis; Radiology; cardiovascular disease; PET imaging; inflammation; Psoriatic arthritis

The aim of the study was to evaluate the changes in central vascular inflammation measured by FDG PET and myocardial blood flow reserve (MFR) determined by 82Rb PET following therapy with biologic agents for 6 months in patients with psoriatic arthritis (PsA) and/or cutaneous psoriasis (PsO) (group...