Propensity Score Matching: Retrospective Randomization?
Randomized controlled trials are viewed as the optimal study design. In this commentary, we explore the strength of this design and its complexity. We also discuss some situations in which these trials are not possible, or not ethical, or not economical. In such situations, specifically, in retrospe...
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| Published in | The Journal of foot and ankle surgery Vol. 56; no. 2; pp. 417 - 420 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.03.2017
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1067-2516 1542-2224 |
| DOI | 10.1053/j.jfas.2017.01.013 |
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| Abstract | Randomized controlled trials are viewed as the optimal study design. In this commentary, we explore the strength of this design and its complexity. We also discuss some situations in which these trials are not possible, or not ethical, or not economical. In such situations, specifically, in retrospective studies, we should make every effort to recapitulate the rigor and strength of the randomized trial. However, we could be faced with an inherent indication bias in such a setting. Thus, we consider the tools available to address that bias. Specifically, we examine matching and introduce and explore a new tool: propensity score matching. This tool allows us to group subjects according to their propensity to be in a particular treatment group and, in so doing, to account for the indication bias. |
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| AbstractList | Randomized controlled trials are viewed as the optimal study design. In this commentary, we explore the strength of this design and its complexity. We also discuss some situations in which these trials are not possible, or not ethical, or not economical. In such situations, specifically, in retrospective studies, we should make every effort to recapitulate the rigor and strength of the randomized trial. However, we could be faced with an inherent indication bias in such a setting. Thus, we consider the tools available to address that bias. Specifically, we examine matching and introduce and explore a new tool: propensity score matching. This tool allows us to group subjects according to their propensity to be in a particular treatment group and, in so doing, to account for the indication bias. Abstract Randomized controlled trials are viewed as the optimal study design. In this commentary, we explore the strength of this design and its complexity. We also discuss some situations in which these trials are not possible, or not ethical, or not economical. In such situations, specifically, in retrospective studies, we should make every effort to recapitulate the rigor and strength of the randomized trial. However, we could be faced with an inherent indication bias in such a setting. Thus, we consider the tools available to address that bias. Specifically, we examine matching and introduce and explore a new tool: propensity score matching. This tool allows us to group subjects according to their propensity to be in a particular treatment group and, in so doing, to account for the indication bias. |
| Author | Jupiter, Daniel C. |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28231973$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1111/iwj.12213 10.1056/NEJMoa1200111 10.4103/0974-1208.82352 10.1053/j.jfas.2016.09.003 10.1053/j.jfas.2013.05.012 10.1053/j.jfas.2016.07.018 |
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| References | Lavery, Higgins, La Fontaine, Zamorano, Constantinides, Kim (bib3) 2015; 12 Jupiter (bib5) 2016; 55 Jupiter (bib1) 2013; 52 Suresh (bib4) 2011; 4 Schweer, Carmouche, Jupiter, Ball, Clements (bib6) 2016; 55 Mingrone, Panuzi, De Gaetano, Guidone, Iaconelli, Leccesi, Nanni, Pomp, Castagneto, Ghirlanda, Rubino (bib2) 2012; 366 Jupiter (10.1053/j.jfas.2017.01.013_bib1) 2013; 52 Mingrone (10.1053/j.jfas.2017.01.013_bib2) 2012; 366 Jupiter (10.1053/j.jfas.2017.01.013_bib5) 2016; 55 Lavery (10.1053/j.jfas.2017.01.013_bib3) 2015; 12 Schweer (10.1053/j.jfas.2017.01.013_bib6) 2016; 55 Suresh (10.1053/j.jfas.2017.01.013_bib4) 2011; 4 |
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| Snippet | Randomized controlled trials are viewed as the optimal study design. In this commentary, we explore the strength of this design and its complexity. We also... Abstract Randomized controlled trials are viewed as the optimal study design. In this commentary, we explore the strength of this design and its complexity. We... |
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| SubjectTerms | Case-Control Studies Humans indication bias Orthopedics Propensity Score propensity score matching Random Allocation randomized controlled trial Randomized Controlled Trials as Topic Research Design |
| Title | Propensity Score Matching: Retrospective Randomization? |
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