Acute Respiratory Illnesses in Children in the SARS-CoV-2 Pandemic: Prospective Multicenter Study
Nonpharmaceutical interventions against coronavirus disease 2019 likely have a role in decreasing viral acute respiratory illnesses (ARIs). We aimed to assess the frequency of respiratory syncytial virus (RSV) and influenza ARIs before and during the coronavirus disease 2019 pandemic. This study was...
Saved in:
| Published in | Pediatrics (Evanston) Vol. 148; no. 2; p. 1 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
American Academy of Pediatrics
01.08.2021
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Nonpharmaceutical interventions against coronavirus disease 2019 likely have a role in decreasing viral acute respiratory illnesses (ARIs). We aimed to assess the frequency of respiratory syncytial virus (RSV) and influenza ARIs before and during the coronavirus disease 2019 pandemic.
This study was a prospective, multicenter, population-based ARI surveillance, including children seen in the emergency departments and inpatient settings in 7 US cities for ARI. Respiratory samples were collected and evaluated by molecular testing. Generalized linear mixed-effects models were used to evaluate the association between community mitigation and number of eligible and proportion of RSV and influenza cases.
Overall, 45 759 children were eligible; 25 415 were enrolled and tested; 25% and 14% were RSV-positive and influenza-positive, respectively. In 2020, we noted a decrease in eligible and enrolled ARI subjects after community mitigation measures were introduced, with no RSV or influenza detection from April 5, 2020, to April 30, 2020. Compared with 2016-2019, there was an average of 10.6 fewer eligible ARI cases per week per site and 63.9% and 45.8% lower odds of patients testing positive for RSV and influenza, respectively, during the 2020 community mitigation period. In all sites except Seattle, the proportions of positive tests for RSV and influenza in the 2020 community mitigation period were lower than predicted.
Between March and April 2020, rapid declines in ARI cases and the proportions of RSV and influenza in children were consistently noted across 7 US cities, which could be attributable to community mitigation measures against severe acute respiratory syndrome coronavirus 2. |
|---|---|
| AbstractList | Nonpharmaceutical interventions against coronavirus disease 2019 likely have a role in decreasing viral acute respiratory illnesses (ARIs). We aimed to assess the frequency of respiratory syncytial virus (RSV) and influenza ARIs before and during the coronavirus disease 2019 pandemic.
This study was a prospective, multicenter, population-based ARI surveillance, including children seen in the emergency departments and inpatient settings in 7 US cities for ARI. Respiratory samples were collected and evaluated by molecular testing. Generalized linear mixed-effects models were used to evaluate the association between community mitigation and number of eligible and proportion of RSV and influenza cases.
Overall, 45 759 children were eligible; 25 415 were enrolled and tested; 25% and 14% were RSV-positive and influenza-positive, respectively. In 2020, we noted a decrease in eligible and enrolled ARI subjects after community mitigation measures were introduced, with no RSV or influenza detection from April 5, 2020, to April 30, 2020. Compared with 2016-2019, there was an average of 10.6 fewer eligible ARI cases per week per site and 63.9% and 45.8% lower odds of patients testing positive for RSV and influenza, respectively, during the 2020 community mitigation period. In all sites except Seattle, the proportions of positive tests for RSV and influenza in the 2020 community mitigation period were lower than predicted.
Between March and April 2020, rapid declines in ARI cases and the proportions of RSV and influenza in children were consistently noted across 7 US cities, which could be attributable to community mitigation measures against severe acute respiratory syndrome coronavirus 2. Nonpharmaceutical interventions against coronavirus disease 2019 likely have a role in decreasing viral acute respiratory illnesses (ARIs). We aimed to assess the frequency of respiratory syncytial virus (RSV) and influenza ARIs before and during the coronavirus disease 2019 pandemic.OBJECTIVESNonpharmaceutical interventions against coronavirus disease 2019 likely have a role in decreasing viral acute respiratory illnesses (ARIs). We aimed to assess the frequency of respiratory syncytial virus (RSV) and influenza ARIs before and during the coronavirus disease 2019 pandemic.This study was a prospective, multicenter, population-based ARI surveillance, including children seen in the emergency departments and inpatient settings in 7 US cities for ARI. Respiratory samples were collected and evaluated by molecular testing. Generalized linear mixed-effects models were used to evaluate the association between community mitigation and number of eligible and proportion of RSV and influenza cases.METHODSThis study was a prospective, multicenter, population-based ARI surveillance, including children seen in the emergency departments and inpatient settings in 7 US cities for ARI. Respiratory samples were collected and evaluated by molecular testing. Generalized linear mixed-effects models were used to evaluate the association between community mitigation and number of eligible and proportion of RSV and influenza cases.Overall, 45 759 children were eligible; 25 415 were enrolled and tested; 25% and 14% were RSV-positive and influenza-positive, respectively. In 2020, we noted a decrease in eligible and enrolled ARI subjects after community mitigation measures were introduced, with no RSV or influenza detection from April 5, 2020, to April 30, 2020. Compared with 2016-2019, there was an average of 10.6 fewer eligible ARI cases per week per site and 63.9% and 45.8% lower odds of patients testing positive for RSV and influenza, respectively, during the 2020 community mitigation period. In all sites except Seattle, the proportions of positive tests for RSV and influenza in the 2020 community mitigation period were lower than predicted.RESULTSOverall, 45 759 children were eligible; 25 415 were enrolled and tested; 25% and 14% were RSV-positive and influenza-positive, respectively. In 2020, we noted a decrease in eligible and enrolled ARI subjects after community mitigation measures were introduced, with no RSV or influenza detection from April 5, 2020, to April 30, 2020. Compared with 2016-2019, there was an average of 10.6 fewer eligible ARI cases per week per site and 63.9% and 45.8% lower odds of patients testing positive for RSV and influenza, respectively, during the 2020 community mitigation period. In all sites except Seattle, the proportions of positive tests for RSV and influenza in the 2020 community mitigation period were lower than predicted.Between March and April 2020, rapid declines in ARI cases and the proportions of RSV and influenza in children were consistently noted across 7 US cities, which could be attributable to community mitigation measures against severe acute respiratory syndrome coronavirus 2.CONCLUSIONSBetween March and April 2020, rapid declines in ARI cases and the proportions of RSV and influenza in children were consistently noted across 7 US cities, which could be attributable to community mitigation measures against severe acute respiratory syndrome coronavirus 2. OBJECTIVES Nonpharmaceutical interventions against coronavirus disease 2019 likely have a role in decreasing viral acute respiratory illnesses (ARIs). We aimed to assess the frequency of respiratory syncytial virus (RSV) and influenza ARIs before and during the coronavirus disease 2019 pandemic. METHODS This study was a prospective, multicenter, population-based ARI surveillance, including children seen in the emergency departments and inpatient settings in 7 US cities for ARI. Respiratory samples were collected and evaluated by molecular testing. Generalized linear mixed-effects models were used to evaluate the association between community mitigation and number of eligible and proportion of RSV and influenza cases. RESULTS Overall, 45 759 children were eligible; 25 415 were enrolled and tested; 25% and 14% were RSV-positive and influenza-positive, respectively. In 2020, we noted a decrease in eligible and enrolled ARI subjects after community mitigation measures were introduced, with no RSV or influenza detection from April 5, 2020, to April 30, 2020. Compared with 2016–2019, there was an average of 10.6 fewer eligible ARI cases per week per site and 63.9% and 45.8% lower odds of patients testing positive for RSV and influenza, respectively, during the 2020 community mitigation period. In all sites except Seattle, the proportions of positive tests for RSV and influenza in the 2020 community mitigation period were lower than predicted. CONCLUSIONS Between March and April 2020, rapid declines in ARI cases and the proportions of RSV and influenza in children were consistently noted across 7 US cities, which could be attributable to community mitigation measures against severe acute respiratory syndrome coronavirus 2. This prospective, multicenter, surveillance study evaluates the frequency of ARI in children before and during the COVID-19 pandemic within seven cities in the United States. |
| Audience | Professional Academic |
| Author | Schuster, Jennifer E. Curns, Aaron T. Klein, Eileen J. Szilagyi, Peter G. Langley, Gayle E. McNeal, Monica Rahman, Herdi Staat, Mary Halasa, Natasha B. Patel, Manish M. Weinberg, Geoffrey A. Stewart, Laura Selvarangan, Rangaraj Lively, Joana Y. Haddadin, Zaid Boom, Julie A. Rha, Brian Williams, John V. Englund, Janet A. Michaels, Marian G. Hall, Aron J. Blozinski, Anna Campbell, Angela P. Harrison, Christopher J. Spieker, Andrew J. Sahni, Leila C. |
| AuthorAffiliation | 13 Department of Pediatrics, Seattle Children’s Hospital, Seattle, WA 9 Department of Pediatrics, University of Cincinnati College of Medicine, Division of Infectious Diseases, Cincinnati Children’s Hospital, Cincinnati, OH 1 Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 7 Department of Pediatrics, Baylor College of Medicine, Houston, TX 11 Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY 4 Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, GA 12 Department of Pediatrics, UCLA Mattel Children’s Hospital, University of California at Los Angeles, Los Angeles, CA 8 Texas Children’s Hospital, Houston, TX 10 Department of Pathology and Laboratory Medicine, University of Missouri – Kansas City, Children’s Mercy Hospital, Kansas City, MO 6 Department of Pediatrics, University of Pittsburgh School of Medicine, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA 3 Department of Biostatistics, Vand |
| AuthorAffiliation_xml | – name: 7 Department of Pediatrics, Baylor College of Medicine, Houston, TX – name: 10 Department of Pathology and Laboratory Medicine, University of Missouri – Kansas City, Children’s Mercy Hospital, Kansas City, MO – name: 1 Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN – name: 8 Texas Children’s Hospital, Houston, TX – name: 12 Department of Pediatrics, UCLA Mattel Children’s Hospital, University of California at Los Angeles, Los Angeles, CA – name: 3 Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN – name: 6 Department of Pediatrics, University of Pittsburgh School of Medicine, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA – name: 9 Department of Pediatrics, University of Cincinnati College of Medicine, Division of Infectious Diseases, Cincinnati Children’s Hospital, Cincinnati, OH – name: 13 Department of Pediatrics, Seattle Children’s Hospital, Seattle, WA – name: 11 Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY – name: 2 Division of Pediatric Infectious Diseases, University of Missouri – Kansas City, Children’s Mercy Hospital, Kansas City, MO – name: 4 Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, GA – name: 5 IHRC, Inc., Atlanta, GA |
| Author_xml | – sequence: 1 givenname: Zaid surname: Haddadin fullname: Haddadin, Zaid organization: Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee – sequence: 2 givenname: Jennifer E. surname: Schuster fullname: Schuster, Jennifer E. organization: Division of Pediatric Infectious Diseases – sequence: 3 givenname: Andrew J. surname: Spieker fullname: Spieker, Andrew J. organization: Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee – sequence: 4 givenname: Herdi surname: Rahman fullname: Rahman, Herdi organization: Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee – sequence: 5 givenname: Anna surname: Blozinski fullname: Blozinski, Anna organization: Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee – sequence: 6 givenname: Laura surname: Stewart fullname: Stewart, Laura organization: Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee – sequence: 7 givenname: Angela P. surname: Campbell fullname: Campbell, Angela P. organization: Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, Georgia – sequence: 8 givenname: Joana Y. surname: Lively fullname: Lively, Joana Y. organization: Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, Georgia, IHRC, Inc, Atlanta, Georgia – sequence: 9 givenname: Marian G. surname: Michaels fullname: Michaels, Marian G. organization: Department of Pediatrics, School of Medicine, University of Pittsburgh and University of Pittsburgh Medical Center Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania – sequence: 10 givenname: John V. surname: Williams fullname: Williams, John V. organization: Department of Pediatrics, School of Medicine, University of Pittsburgh and University of Pittsburgh Medical Center Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania – sequence: 11 givenname: Julie A. surname: Boom fullname: Boom, Julie A. organization: Department of Pediatrics, Baylor College of Medicine, Houston, Texas, Texas Children's Hospital, Houston, Texas – sequence: 12 givenname: Leila C. surname: Sahni fullname: Sahni, Leila C. organization: Department of Pediatrics, Baylor College of Medicine, Houston, Texas, Texas Children's Hospital, Houston, Texas – sequence: 13 givenname: Mary surname: Staat fullname: Staat, Mary organization: Department of Pediatrics, College of Medicine, University of Cincinnati and Division of Infectious Diseases, Cincinnati Children’s Hospital, Cincinnati, Ohio – sequence: 14 givenname: Monica surname: McNeal fullname: McNeal, Monica organization: Department of Pediatrics, College of Medicine, University of Cincinnati and Division of Infectious Diseases, Cincinnati Children’s Hospital, Cincinnati, Ohio – sequence: 15 givenname: Rangaraj surname: Selvarangan fullname: Selvarangan, Rangaraj organization: Division of Pediatric Infectious Diseases, Department of Pathology and Laboratory Medicine, University of Missouri-Kansas City and Children's Mercy Hospital, Kansas City, Missouri – sequence: 16 givenname: Christopher J. surname: Harrison fullname: Harrison, Christopher J. organization: Division of Pediatric Infectious Diseases – sequence: 17 givenname: Geoffrey A. surname: Weinberg fullname: Weinberg, Geoffrey A. organization: Department of Pediatrics, School of Medicine and Dentistry, University of Rochester, Rochester, New York – sequence: 18 givenname: Peter G. surname: Szilagyi fullname: Szilagyi, Peter G. organization: Department of Pediatrics, School of Medicine and Dentistry, University of Rochester, Rochester, New York, Department of Pediatrics, University of California at Los Angeles Mattel Children’s Hospital and University of California at Los Angeles, Los Angeles, California – sequence: 19 givenname: Janet A. surname: Englund fullname: Englund, Janet A. organization: Department of Pediatrics, Seattle Children’s Hospital, Seattle, Washington – sequence: 20 givenname: Eileen J. surname: Klein fullname: Klein, Eileen J. organization: Department of Pediatrics, Seattle Children’s Hospital, Seattle, Washington – sequence: 21 givenname: Aaron T. surname: Curns fullname: Curns, Aaron T. organization: Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, Georgia – sequence: 22 givenname: Brian surname: Rha fullname: Rha, Brian organization: Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, Georgia – sequence: 23 givenname: Gayle E. surname: Langley fullname: Langley, Gayle E. organization: Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, Georgia – sequence: 24 givenname: Aron J. surname: Hall fullname: Hall, Aron J. organization: Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, Georgia – sequence: 25 givenname: Manish M. surname: Patel fullname: Patel, Manish M. organization: Centers for Disease Control and Prevention COVID-19 Response Team, Atlanta, Georgia – sequence: 26 givenname: Natasha B. surname: Halasa fullname: Halasa, Natasha B. organization: Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33986150$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1ks1rGzEQxUVJaT7ae09loZdeNh1ptVptDwVj-hFISYjbXoUsz9oKsuRI2lD_99XiNLSBniSY3zzezLxTcuSDR0JeUzinLWfvd7hK5wwYraGlXLBn5IRCL2vOuvaInAA0tOYA7TE5TekWAHjbsRfkuGl6KWgLJ0TPzJixusG0s1HnEPfVhXMeU8JUWV_NN9atIvrpnzdYLWY3i3oeftasutZ-hVtrPlTXMaQdmmzvsfo2umwN-oyxWuRxtX9Jng_aJXz18J6RH58_fZ9_rS-vvlzMZ5e1aZnMdW94N7CuWEYGSy4oBcmWkplBatOA7HTTcCGoMLrUWWc6PjDDl3o5CM6xa87Ix4PublxucTVZiNqpXbRbHfcqaKv-rXi7Uetwr2TTyB5EEXj3IBDD3Ygpq61NBp3THsOYFCs-aYEZFPTtE_Q2jNGX8QolgEPXgyxUfaDW2qGy3oSylV_ZBOdwjapMP79SMyEla_q2nVTf_D3Bo_U_1yoAHABTFp4iDo8IBTUFQk2BUFMg1CEQpUU8aTE262zDtAPr_t_4G_gduPw |
| CitedBy_id | crossref_primary_10_7189_jogh_11_01010 crossref_primary_10_3390_jcm14041387 crossref_primary_10_1097_INF_0000000000004575 crossref_primary_10_3201_eid1801_211099 crossref_primary_10_1002_ppul_26328 crossref_primary_10_2139_ssrn_4186726 crossref_primary_10_5005_jp_journals_11002_0073 crossref_primary_10_1001_jamanetworkopen_2023_28950 crossref_primary_10_1017_ice_2022_137 crossref_primary_10_3390_tropicalmed7080151 crossref_primary_10_1093_infdis_jiab620 crossref_primary_10_1017_S1047951124036047 crossref_primary_10_1080_15563650_2022_2158847 crossref_primary_10_1093_infdis_jiae295 crossref_primary_10_15585_mmwr_mm7029a1 crossref_primary_10_3390_diagnostics12051208 crossref_primary_10_3399_bjgp21X717221 crossref_primary_10_1017_ash_2022_235 crossref_primary_10_3389_fviro_2023_1156012 crossref_primary_10_1002_jpn3_70009 crossref_primary_10_3201_eid2801_211099 crossref_primary_10_1016_j_jpedsurg_2023_02_004 crossref_primary_10_20344_amp_19642 crossref_primary_10_1093_cid_ciad458 crossref_primary_10_1093_cid_ciac487 crossref_primary_10_1177_19418744221123208 crossref_primary_10_1186_s12887_022_03549_y crossref_primary_10_1038_s41598_023_48814_x crossref_primary_10_1093_infdis_jiad417 crossref_primary_10_2196_49170 crossref_primary_10_3390_antibiotics11020264 crossref_primary_10_1002_hsr2_1787 crossref_primary_10_1016_j_pedn_2022_10_008 crossref_primary_10_1016_j_jpeds_2025_114538 crossref_primary_10_3389_fped_2023_1240242 crossref_primary_10_3390_v17030389 crossref_primary_10_1186_s12879_023_08687_x crossref_primary_10_1542_peds_2022_059235 crossref_primary_10_1542_peds_2023_062574 crossref_primary_10_1001_jamanetworkopen_2022_54909 crossref_primary_10_2196_43941 crossref_primary_10_2169_internalmedicine_3266_23 crossref_primary_10_1093_jpids_piac066 crossref_primary_10_3390_antibiotics11060746 crossref_primary_10_1093_jpids_piab098 crossref_primary_10_1001_jamanetworkopen_2023_50061 crossref_primary_10_1038_s41598_022_21430_x crossref_primary_10_1097_INF_0000000000003981 crossref_primary_10_1186_s12879_023_08247_3 crossref_primary_10_3389_fped_2023_1198278 crossref_primary_10_1136_bmjopen_2022_067878 crossref_primary_10_1007_s00705_023_05698_6 crossref_primary_10_1093_cid_ciae573 crossref_primary_10_1002_jmv_28439 crossref_primary_10_3390_children9040513 crossref_primary_10_1016_j_jiph_2023_09_015 crossref_primary_10_1038_s41579_022_00807_9 crossref_primary_10_1186_s40249_024_01218_z crossref_primary_10_1001_jamanetworkopen_2023_13354 crossref_primary_10_1016_j_arbres_2024_05_019 crossref_primary_10_1016_j_jpeds_2023_113475 crossref_primary_10_1016_j_jiac_2023_11_012 crossref_primary_10_1016_j_jcv_2022_105220 crossref_primary_10_1371_journal_pone_0270469 crossref_primary_10_1093_cid_ciac942 crossref_primary_10_1111_ajt_16049 crossref_primary_10_15585_mmwr_mm7140a1 crossref_primary_10_1515_labmed_2021_0128 crossref_primary_10_7759_cureus_28559 crossref_primary_10_1093_pch_pxad037 crossref_primary_10_1080_07370016_2025_2452164 crossref_primary_10_1186_s12889_022_14299_y crossref_primary_10_1016_j_jtct_2023_09_018 crossref_primary_10_31508_1676_379320220024 |
| Cites_doi | 10.1093/ofid/ofaa511 10.15585/mmwr.mm6919e2 10.15585/mmwr.mm6915e2 10.1542/peds.2013-0303 10.1186/cc12512 10.15585/mmwr.rr6601a1 10.1136/bmjopen-2018-021898 10.1056/NEJMp2003539 10.1542/peds.2019-3611 10.1086/649867 10.1056/NEJMoa1405870 10.15585/mmwr.mm6923e1 10.1001/jama.298.6.644 10.1073/pnas.2013182117 10.15585/mmwr.mm6945e1 10.1183/23120541.00296-2020 10.1007/s00431-004-1580-0 10.1073/pnas.0900933106 10.1136/bmj.m1066 10.1016/j.tmaid.2020.101803 10.1126/science.1260612 10.1001/jama.2020.6173 10.1056/NEJMoa2001316 10.15585/mmwr.mm6920e1 10.15585/mmwr.mm6937a6 10.1056/NEJMp2005835 10.15585/mmwr.mm6702a4 10.1542/peds.2020-1368 |
| ContentType | Journal Article |
| Copyright | Copyright © 2021 by the American Academy of Pediatrics. COPYRIGHT 2021 American Academy of Pediatrics Copyright American Academy of Pediatrics Aug 1, 2021 |
| Copyright_xml | – notice: Copyright © 2021 by the American Academy of Pediatrics. – notice: COPYRIGHT 2021 American Academy of Pediatrics – notice: Copyright American Academy of Pediatrics Aug 1, 2021 |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7TS 7U9 H94 K9. M7N NAPCQ U9A 7X8 5PM |
| DOI | 10.1542/peds.2021-051462 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Physical Education Index Virology and AIDS Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Algology Mycology and Protozoology Abstracts (Microbiology C) Nursing & Allied Health Premium MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Nursing & Allied Health Premium Virology and AIDS Abstracts Algology Mycology and Protozoology Abstracts (Microbiology C) AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Physical Education Index Career and Technical Education (Alumni Edition) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic Nursing & Allied Health Premium |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1098-4275 |
| ExternalDocumentID | PMC8338906 A688239550 33986150 10_1542_peds_2021_051462 |
| Genre | Journal Article Research Support, N.I.H., Extramural |
| GeographicLocations | United States United States--US |
| GeographicLocations_xml | – name: United States – name: United States--US |
| GrantInformation_xml | – fundername: NCIRD CDC HHS grantid: U01 IP001156 – fundername: NCIRD CDC HHS grantid: U01 IP001049 – fundername: NCIRD CDC HHS grantid: U01 IP001158 – fundername: NCIRD CDC HHS grantid: U01 IP001050 – fundername: NCATS NIH HHS grantid: UL1 TR000445 – fundername: NCIRD CDC HHS grantid: U01 IP001063 – fundername: NCIRD CDC HHS grantid: U01 IP001157 |
| GroupedDBID | --- -ET ..I .55 0R~ 123 18M 1HT 26- 29O 2WC 36B 39C 4.4 53G 5RE 5VS 6PF 7K8 85S 8F7 96U AAAMJ AAHTB AAIKC AAJMC AAMNW AAWTL AAWTO AAYXX ABCZD ABIVO ABJNI ABOCM ABPEJ ABPPZ ACBMB ACGFO ACGOD ACNCT ACPRK ADCOW AENEX AFAZI AFHKK AFOSN AFRAH AGFXO AHMBA ALMA_UNASSIGNED_HOLDINGS CITATION CS3 DIK DU5 E3Z EBS F5P F8P GX1 H13 HF~ IAO IOF KO8 KQ8 L7B LXN N9A OK1 P0W P2P PDE PQQKQ Q.- RHI SJN TAE TR2 TWZ UBE W8F WH7 WOQ WQ9 X7M XZL YHG YHZ YOC YZZ ZRR ~KM .GJ 1CY 2KS 2QL 41~ 8GL AAKAS AAQOH ADZCM AFFNX AJUXI BKOMP CGR CUY CVF ECM EIF EJD EX3 FEDTE GICCO GOZPB HVGLF IAG ICJ IEA IER IHR IMI INH INR IPO IPY ISE ITC IVC LXL LXY N4W NEJ NPM OHT OMK OVD TEORI UHB UMD WHG WOW XJT XOL YQI YQJ ZGI ZXP ~X8 7TS 7U9 H94 K9. M7N NAPCQ U9A 7X8 5PM |
| ID | FETCH-LOGICAL-c528t-9c47f27003e20b4611082b82cf8ac3087a3346616ca20b27c74f2c4babf644e73 |
| ISSN | 0031-4005 1098-4275 |
| IngestDate | Thu Aug 21 18:31:19 EDT 2025 Sun Aug 24 03:18:49 EDT 2025 Fri Jul 25 10:06:20 EDT 2025 Wed Mar 12 00:55:48 EDT 2025 Tue Jul 22 01:41:59 EDT 2025 Tue Jul 01 01:10:37 EDT 2025 Thu Apr 24 22:56:52 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 2 |
| Language | English |
| License | Copyright © 2021 by the American Academy of Pediatrics. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c528t-9c47f27003e20b4611082b82cf8ac3087a3346616ca20b27c74f2c4babf644e73 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 Mr. Curns contributed significantly to acquisition of data, and revised the manuscript critically for important intellectual content. Contributors’ Statement Page Mr. Rahman, Ms. Blozinski and Dr. Andrew Spieker performed and supervised data analysis, and reviewed and revised the manuscript. Dr. Hall contributed significantly to conception and design of the study, interpretation of data and revised the manuscript critically for important intellectual content. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. Drs. Schuster, Stewart, Campbell, Michaels, Williams, Boom, Sahni, Staat, McNeal, Selvarangan, Harrison, Weinberg, Szilagyi, Englund, Klein, Rha, Langley, Patel and Halasa and Ms. Lively conceptualized and designed the study, designed the data collection instruments, coordinated and supervised data collection and testing, and reviewed and revised the manuscript. Dr. Haddadin, conceptualized and designed the study, performed the initial analyses, drafted the initial manuscript, and reviewed and revised the manuscript. |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/8338906 |
| PMID | 33986150 |
| PQID | 2560407908 |
| PQPubID | 47366 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_8338906 proquest_miscellaneous_2528183320 proquest_journals_2560407908 gale_incontextcollege_GICCO_A688239550 pubmed_primary_33986150 crossref_primary_10_1542_peds_2021_051462 crossref_citationtrail_10_1542_peds_2021_051462 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2021-08-01 |
| PublicationDateYYYYMMDD | 2021-08-01 |
| PublicationDate_xml | – month: 08 year: 2021 text: 2021-08-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Evanston |
| PublicationTitle | Pediatrics (Evanston) |
| PublicationTitleAlternate | Pediatrics |
| PublicationYear | 2021 |
| Publisher | American Academy of Pediatrics |
| Publisher_xml | – name: American Academy of Pediatrics |
| References | Khuri-Bulos (2021121007442979200_B31) 2018; 8 Jain (2021121007442979200_B28) 2015; 372 Rose (2021121007442979200_B14) 2018; 67 Olsen (2021121007442979200_B8) 2020; 69 Parry (2021121007442979200_B9) 2020; 7 Baker (2021121007442979200_B26) 2020; 117 Ebrahim (2021121007442979200_B2) 2020; 368 Markel (2021121007442979200_B23) 2007; 298 Lasry (2021121007442979200_B20) 2020; 69 Qualls (2021121007442979200_B3) 2017; 66 Hall (2021121007442979200_B17) 2013; 132 Campbell (2021121007442979200_B18) 2020; 146 Hartnett (2021121007442979200_B27) 2020; 69 Santoli (2021121007442979200_B13) 2020; 69 Pandey (2021121007442979200_B21) 2014; 346 Sakamoto (2021121007442979200_B6) 2020; 323 Kanu (2021121007442979200_B4) 2020; 69 Young (2021121007442979200_B25) 2020; 6 Lipsitch (2021121007442979200_B15) 2009; 106 Rosenberg (2021121007442979200_B24) 2020; 72 Zangrillo (2021121007442979200_B29) 2013; 17 Perlroth (2021121007442979200_B22) 2010; 50 Haddadin (2021121007442979200_B16) Angoulvant (2021121007442979200_B7) 2020 Bramer (2021121007442979200_B12) 2020; 69 Hollander (2021121007442979200_B11) 2020; 382 Flamant (2021121007442979200_B30) 2005; 164 Keesara (2021121007442979200_B10) 2020; 382 Hong (2021121007442979200_B5) 2020; 36 Rha (2021121007442979200_B19) 2020; 146 Li (2021121007442979200_B1) 2020; 382 |
| References_xml | – volume: 7 start-page: ofaa511 issue: 11 year: 2020 ident: 2021121007442979200_B9 article-title: Precipitous fall in common respiratory viral infections during COVID-19 publication-title: Open Forum Infect Dis doi: 10.1093/ofid/ofaa511 – volume: 72 start-page: 144 issue: 1 year: 2020 ident: 2021121007442979200_B24 article-title: Monitoring COVID-19 through trends in Influenza-like illness, laboratory-confirmed influenza, and COVID-19 - New York State, excluding New York City, 1 January 2020-12 April 2020 publication-title: Clin Infect Dis – volume: 69 start-page: 591 issue: 19 year: 2020 ident: 2021121007442979200_B13 article-title: Effects of the COVID-19 pandemic on routine pediatric vaccine ordering and administration - United States, 2020 publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm6919e2 – volume: 69 start-page: 451 issue: 15 year: 2020 ident: 2021121007442979200_B20 article-title: Timing of community mitigation and changes in reported COVID-19 and community mobility—four US metropolitan areas, February 26–April 1, 2020 publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm6915e2 – volume: 132 start-page: e341 issue: 2 year: 2013 ident: 2021121007442979200_B17 article-title: Respiratory syncytial virus-associated hospitalizations among children less than 24 months of age publication-title: Pediatrics doi: 10.1542/peds.2013-0303 – volume: 17 start-page: R30 issue: 1 year: 2013 ident: 2021121007442979200_B29 article-title: Extracorporeal membrane oxygenation (ECMO) in patients with H1N1 influenza infection: a systematic review and meta-analysis including 8 studies and 266 patients receiving ECMO publication-title: Crit Care doi: 10.1186/cc12512 – volume: 66 start-page: 1 issue: 1 year: 2017 ident: 2021121007442979200_B3 article-title: Community mitigation guidelines to prevent pandemic influenza - United States, 2017 publication-title: MMWR Recomm Rep doi: 10.15585/mmwr.rr6601a1 – volume: 8 start-page: e021898 issue: 5 year: 2018 ident: 2021121007442979200_B31 article-title: Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan publication-title: BMJ Open doi: 10.1136/bmjopen-2018-021898 – volume: 382 start-page: 1679 issue: 18 year: 2020 ident: 2021121007442979200_B11 article-title: Virtually perfect? Telemedicine for Covid-19 publication-title: N Engl J Med doi: 10.1056/NEJMp2003539 – volume: 146 start-page: e20193611 issue: 1 year: 2020 ident: 2021121007442979200_B19 article-title: Respiratory syncytial virus-associated hospitalizations among young children: 2015-2016 publication-title: Pediatrics doi: 10.1542/peds.2019-3611 – volume: 50 start-page: 165 issue: 2 year: 2010 ident: 2021121007442979200_B22 article-title: Health outcomes and costs of community mitigation strategies for an influenza pandemic in the United States publication-title: Clin Infect Dis doi: 10.1086/649867 – volume: 372 start-page: 835 issue: 9 year: 2015 ident: 2021121007442979200_B28 article-title: Community-acquired pneumonia requiring hospitalization among U.S. children publication-title: N Engl J Med doi: 10.1056/NEJMoa1405870 – volume: 69 start-page: 699 issue: 23 year: 2020 ident: 2021121007442979200_B27 article-title: Impact of the COVID-19 pandemic on emergency department visits - United States, January 1, 2019-May 30, 2020 publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm6923e1 – volume: 298 start-page: 644 issue: 6 year: 2007 ident: 2021121007442979200_B23 article-title: Nonpharmaceutical interventions implemented by US cities during the 1918-1919 influenza pandemic publication-title: JAMA doi: 10.1001/jama.298.6.644 – volume: 117 start-page: 30547 issue: 48 year: 2020 ident: 2021121007442979200_B26 article-title: The impact of COVID-19 nonpharmaceutical interventions on the future dynamics of endemic infections publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.2013182117 – volume: 69 start-page: 1691 issue: 45 year: 2020 ident: 2021121007442979200_B4 article-title: Declines in SARS-CoV-2 transmission, hospitalizations, and mortality After implementation of mitigation measures- Delaware, March-June 2020 publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm6945e1 – start-page: ciaa710 year: 2020 ident: 2021121007442979200_B7 article-title: COVID-19 pandemic: impact caused by school closure and national lockdown on pediatric visits and admissions for viral and non-viral infections, a time series analysis publication-title: Clin Infect Dis – ident: 2021121007442979200_B16 article-title: Respiratory syncytial virus disease severity in young children [published online ahead of print October 23, 2020] publication-title: Clin Infect Dis – volume: 6 issue: 3 year: 2020 ident: 2021121007442979200_B25 article-title: Rapid decline of seasonal influenza during the outbreak of COVID-19 publication-title: ERJ Open Res doi: 10.1183/23120541.00296-2020 – volume: 164 start-page: 93 issue: 2 year: 2005 ident: 2021121007442979200_B30 article-title: Severe respiratory syncytial virus bronchiolitis in children: from short mechanical ventilation to extracorporeal membrane oxygenation publication-title: Eur J Pediatr doi: 10.1007/s00431-004-1580-0 – volume: 106 start-page: 3645 issue: 10 year: 2009 ident: 2021121007442979200_B15 article-title: Influenza seasonality: lifting the fog publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0900933106 – volume: 368 start-page: m1066 year: 2020 ident: 2021121007442979200_B2 article-title: Covid-19 and community mitigation strategies in a pandemic publication-title: BMJ doi: 10.1136/bmj.m1066 – volume: 36 start-page: 101803 year: 2020 ident: 2021121007442979200_B5 article-title: Mask wearing in pre-symptomatic patients prevents SARS-CoV-2 transmission: an epidemiological analysis publication-title: Travel Med Infect Dis doi: 10.1016/j.tmaid.2020.101803 – volume: 346 start-page: 991 issue: 6212 year: 2014 ident: 2021121007442979200_B21 article-title: Strategies for containing Ebola in West Africa publication-title: Science doi: 10.1126/science.1260612 – volume: 323 start-page: 1969 issue: 19 year: 2020 ident: 2021121007442979200_B6 article-title: Seasonal influenza activity during the SARS-CoV-2 outbreak in Japan publication-title: JAMA doi: 10.1001/jama.2020.6173 – volume: 382 start-page: 1199 issue: 13 year: 2020 ident: 2021121007442979200_B1 article-title: Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia publication-title: N Engl J Med doi: 10.1056/NEJMoa2001316 – volume: 69 start-page: 630 issue: 20 year: 2020 ident: 2021121007442979200_B12 article-title: Decline in child vaccination coverage during the COVID-19 pandemic - Michigan Care Improvement Registry, May 2016-May 2020 publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm6920e1 – volume: 69 start-page: 1305 issue: 37 year: 2020 ident: 2021121007442979200_B8 article-title: Decreased influenza activity during the COVID-19 pandemic - United States, Australia, Chile, and South Africa, 2020 publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm6937a6 – volume: 382 start-page: e82 issue: 23 year: 2020 ident: 2021121007442979200_B10 article-title: Covid-19 and health care’s digital revolution publication-title: N Engl J Med doi: 10.1056/NEJMp2005835 – volume: 67 start-page: 71 issue: 2 year: 2018 ident: 2021121007442979200_B14 article-title: Respiratory syncytial virus seasonality - United States, 2014-2017 publication-title: MMWR Morb Mortal Wkly Rep doi: 10.15585/mmwr.mm6702a4 – volume: 146 start-page: e20201368 issue: 5 year: 2020 ident: 2021121007442979200_B18 article-title: Vaccine effectiveness against pediatric influenza hospitalizations and emergency visits publication-title: Pediatrics doi: 10.1542/peds.2020-1368 |
| SSID | ssj0004572 |
| Score | 2.6077344 |
| Snippet | Nonpharmaceutical interventions against coronavirus disease 2019 likely have a role in decreasing viral acute respiratory illnesses (ARIs). We aimed to assess... OBJECTIVES Nonpharmaceutical interventions against coronavirus disease 2019 likely have a role in decreasing viral acute respiratory illnesses (ARIs). We aimed... This prospective, multicenter, surveillance study evaluates the frequency of ARI in children before and during the COVID-19 pandemic within seven cities in the... |
| SourceID | pubmedcentral proquest gale pubmed crossref |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 1 |
| SubjectTerms | Adolescent Child Child, Preschool Children Comorbidity Company distribution practices Coronaviruses COVID-19 COVID-19 - epidemiology Diagnosis Diseases Distribution Emergency medical care Epidemics Follow-Up Studies Humans Infant Influence Influenza Male Pandemics Pediatric diseases Pediatrics Population Surveillance Prospective Studies Respiratory diseases Respiratory syncytial virus Respiratory syncytial virus infection Respiratory Tract Infections - epidemiology SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 United States United States - epidemiology |
| Title | Acute Respiratory Illnesses in Children in the SARS-CoV-2 Pandemic: Prospective Multicenter Study |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/33986150 https://www.proquest.com/docview/2560407908 https://www.proquest.com/docview/2528183320 https://pubmed.ncbi.nlm.nih.gov/PMC8338906 |
| Volume | 148 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1da9swFBWhg9KXse9564YGYzCCW0dS_LG3EDqyjm5d2o6-GUmxSCFzQkhe9ut3r2Qrcilj64sxkSw5vsfyvbpHR4S8nw35TCQAXpYaEwudprFiehBXUs1yJWdCGUuQ_ZZOrsTp9fC61wtZS9uNOtK_71xXch-rwm9gV1wl-x-W9Y3CD3AO9oUjWBiO_2TjkcYs_zTIln9ZLHDssiwrJ1uMC7UbLuPFaHoRj5c_YwaOY21p8TghcL5etust-3Y9LhI2q7WlGHaSvn5bDztTa31w6zkW4TCGnHyb8ZAtVx6zPPNtuwNIS6fpnxyFmfuG3OH4lf1TXzaV82aOdlIBlsNJCjbwFDk_8HIMVROXwK7cWItSpoK5jVP8YCzyAHXszkF-KFA0dlXNUG4d-wKnL-1UhYe3-mWNznmRo-b97nPnSYjnZ-McAvQCBdsfMIgycAOMrz9CsfnMic03995kuaH749udH5D9tqeOg3P7Mx_4OV0ObuDUXD4iD5tohI4ctB6TXlU_IftnDd_iKZEWYTRAGPUIozc1bRGG54AwukMYbRH2iQb4ogG-qMXXM3L1-eRyPImbTTliPWT5Ji60yAyyFXjFEiVSXEbCVM60yaVGeUnJuQCnL9USylmmM2GYFkoqA653lfHnZK9e1tVLQtPE5MwoYRIjhc4NBANDnSUDaFXCuY7IcfskS90o1uPGKYsSI1cwQ4lmKNEMpTNDRD76K1ZOreUvdT-gcUoUQamRZaXdTF0J_3b8vRylEHvyAgL4iBy25iublx8agkhBJFmR5BF554thaMZ8m6yr5RbroNQa5wyaeOGs7e-qRUtEsg4OfAWUfe-W1DdzK__egPbVva98TQ527-gh2dust9UbcK036q19Af4AJ47MUQ |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Acute+Respiratory+Illnesses+in+Children+in+the+SARS-CoV-2+Pandemic%3A+Prospective+Multicenter+Study&rft.jtitle=Pediatrics+%28Evanston%29&rft.au=Haddadin%2C+Zaid&rft.au=Schuster%2C+Jennifer+E.&rft.au=Spieker%2C+Andrew+J.&rft.au=Rahman%2C+Herdi&rft.date=2021-08-01&rft.issn=0031-4005&rft.eissn=1098-4275&rft.volume=148&rft.issue=2&rft_id=info:doi/10.1542%2Fpeds.2021-051462&rft_id=info%3Apmid%2F33986150&rft.externalDocID=PMC8338906 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0031-4005&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0031-4005&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0031-4005&client=summon |