The CCAAT/Enhancer-Binding Protein Family: Its Roles in MDSC Expansion and Function

• Published in: Frontiers in immunology Vol. 10; p. 1804
• Main Authors: Wang, Wenxin, Xia, Xueli, Mao, Lingxiang, Wang, Shengjun
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 31.07.2019
• Subjects: C/EBPs; differentiation; Immunology; immunosuppression; myeloid-derived suppressor cells; transcription factors; immunosuppression; differentiation; transcription factors; myeloid-derived suppressor cells; C/EBPs

Immunosuppressive cells have been highlighted in research due to their roles in tumor progression and treatment failure. Myeloid-derived suppressor cells (MDSCs) are among the major immunosuppressive cell populations in the tumor microenvironment, and transcription factors (TFs) are likely involved...