Gene Signatures and Prognostic Values of m6A RNA Methylation Regulators in Ovarian Cancer

• Published in: Cancer control Vol. 27; no. 1; p. 1073274820960460
• Main Authors: Han, Xiao, Liu, Jie, Cheng, Guomei, Cui, Shihong
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.01.2020; Sage Publications Ltd; SAGE Publishing
• Subjects: Adenosine - analogs & derivatives; Adenosine - chemistry; Bioinformatics; Biomarkers, Tumor - genetics; Cell cycle; Cell Cycle Proteins - genetics; Copy number; DNA Methylation; Epigenetics; Female; Follow-Up Studies; Gene expression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene set enrichment analysis; Humans; Middle Aged; Myc protein; N6-methyladenosine; Original Research Paper; Ovarian cancer; Ovarian Neoplasms - genetics; Ovarian Neoplasms - pathology; Prognosis; Retrospective Studies; RNA modification; RNA Splicing Factors - genetics; Survival Rate; N6-methyladenosine; biomarker; ovarian cancer; PROGNOSIS; bioinformatics

Background: N6-methyladenosine (m6A) is the most common form of mRNA modification under the field of “RNA epigenetics.” However, its role in ovarian cancer (OC) development is poorly understood. In the current study, we aimed to identify gene signatures and prognostic values of m6A RNA methylation r...