Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies

• Published in: Frontiers in genetics Vol. 10; p. 24
• Main Authors: Zur Lage, Petra, Newton, Fay G, Jarman, Andrew P
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 01.02.2019
• Subjects: ciliopathy; cilium; Drosophila; dynein; flagellum; Genetics; dynein; cilium; flagellum; Drosophila; ciliopathy

The motile cilium/flagellum is an ancient eukaryotic organelle. The molecular machinery of ciliary motility comprises a variety of cilium-specific dynein motor complexes along with other complexes that regulate their activity. Assembling the motors requires the function of dedicated "assembly f...