Long-Term Outcomes of BMMSC Compared with BMMNC for Treatment of Critical Limb Ischemia and Foot Ulcer in Patients with Diabetes

• Published in: Cell transplantation Vol. 28; no. 5; pp. 645 - 652
• Main Authors: Lu, Debin, Jiang, Youzhao, Deng, Wuquan, Zhang, Yan, Liang, Ziwen, Wu, Qinan, Jiang, Xiaoyan, Zhang, Ling, Gao, Fang, Cao, Ying, Chen, Bing, Xue, Yaoming
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.05.2019; Sage Publications Ltd; SAGE Publishing
• Subjects: Amputation; Autografts; Blood flow; Bone marrow transplantation; Diabetes; Diabetes mellitus; Feet; Ischemia; Leg ulcers; Mesenchyme; Original; Patients; Stem cell transplantation; Stem cells; Transplants & implants; clinical trial; autologous transplantation; cellular therapy; critical limb; diabetes; ischemia

We first compared long-term clinical outcomes in treating critical limb ischemia (CLI) and foot ulcer in patients with diabetes between autologous bone marrow mesenchymal stem cell (BMMSC) and bone-marrow-derived mononuclear cell (BMMNC) transplants. Forty-one patients were enrolled and followed up...