Lysozyme gene treatment in testosterone induced benign prostate hyperplasia rat model and comparasion of its' effectiveness with botulinum toxin injection

• Published in: International Brazilian Journal of Urology Vol. 43; no. 6; pp. 1167 - 1175
• Main Authors: Ergün, Osman, Koşar, Pinar Aslan, Onaran, İbrahim, Darici, Hakan, Koşar, Alim
• Format: Journal Article
• Language: English
• Published: Brazil Sociedade Brasileira de Urologia 01.11.2017
• Subjects: Animals; Botulinum Toxins; Botulinum Toxins, Type A - therapeutic use; Disease Models, Animal; Genetic Therapy - methods; Male; Muramidase - genetics; Original; Prostatic Hyperplasia; Prostatic Hyperplasia - chemically induced; Prostatic Hyperplasia - drug therapy; Rats; Rats, Wistar; Testosterone; Botulinum Toxins; Prostatic Hyperplasia; Testosterone

To compare the effects and histopathological changes of botulinum neurotoxin type A and lysozyme gene injections into prostate tissue within a testosterone induced benign prostate hyperplasia rat model. 40 male Wistar rats were randomized into four Groups. Group-1: Control, Group-2: Testosterone rep...