Effect of gabapentin on sexual function in vulvodynia: a randomized, placebo-controlled trial

• Published in: American journal of obstetrics and gynecology Vol. 220; no. 1; pp. 89.e1 - 89.e8
• Main Authors: Bachmann, Gloria A., Brown, Candace S., Phillips, Nancy A., Rawlinson, Leslie A., Yu, Xinhua, Wood, Ronald, Foster, David C., Dawicki, Diane, Bonham, Adrienne, Dworkin, Robert, Balabathula, Pavan, Bachour, Candi, Brooks, Ian, Dulin, Turid, Horton, Frank, Sakauye, Mark, Thoma, Laura, Villa, Emanuel, Wang, Jiajing, Ling, Frank, Nyirjesy, Paul, Fosbre, Sue, Hartmann, Dianne, Queenen, John, Pulsinelli, William, Taylor, Deanne, Wesselmann, Ursula
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.01.2019
• Subjects: Adult; Confidence Intervals; Cross-Over Studies; Delayed-Action Preparations - therapeutic use; Double-Blind Method; Female; gabapentin; Gabapentin - therapeutic use; Humans; Middle Aged; Pain Measurement; Patient Satisfaction - statistics & numerical data; pelvic floor; Pelvic Floor - physiopathology; Prognosis; Reference Values; Risk Assessment; Severity of Illness Index; Sexual Dysfunction, Physiological - drug therapy; sexual function; Treatment Outcome; vulvodynia; Vulvodynia - drug therapy; Vulvodynia - prevention & control; vulvodynia; sexual function; pelvic floor; gabapentin

Sexual dysfunction is common in women with vulvodynia. The purpose of this study was (1) to evaluate whether extended-release gabapentin is more effective than placebo in improving sexual function in women with provoked vulvodynia and whether there is a relationship between treatment outcome and pel...