Evaluation of pulmonary and systemic toxicity following lung exposure to graphite nanoplates: a member of the graphene-based nanomaterial family

• Published in: Particle and fibre toxicology Vol. 13; no. 1; p. 34
• Main Authors: Roberts, Jenny R, Mercer, Robert R, Stefaniak, Aleksandr B, Seehra, Mohindar S, Geddam, Usha K, Chaudhuri, Ishrat S, Kyrlidis, Angelos, Kodali, Vamsi K, Sager, Tina, Kenyon, Allison, Bilgesu, Suzan A, Eye, Tracy, Scabilloni, James F, Leonard, Stephen S, Fix, Natalie R, Schwegler-Berry, Diane, Farris, Breanne Y, Wolfarth, Michael G, Porter, Dale W, Castranova, Vincent, Erdely, Aaron
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.06.2016; BioMed Central
• Subjects: Animals; Bronchoalveolar Lavage Fluid; Carbon black; Causes of; Chemical properties; Electrons; Graphene; Graphite; Graphite - toxicity; Lung - drug effects; Lung - metabolism; Mice; Microscopy, Electron, Scanning; Nanomaterials; Nanoparticles; Nanostructures - toxicity; Physiological aspects; RNA, Messenger - metabolism; Toxicity; United States; Lung toxicity; Pulmonary exposure; Graphene-based nanomaterials; Particle size; Cardiovascular toxicity

Graphene, a monolayer of carbon, is an engineered nanomaterial (ENM) with physical and chemical properties that may offer application advantages over other carbonaceous ENMs, such as carbon nanotubes (CNT). The goal of this study was to comparatively assess pulmonary and systemic toxicity of graphit...