Accuracy of arterial [18F]-Fluorodeoxyglucose uptake quantification: A kinetic modeling study

• Published in: Journal of nuclear cardiology Vol. 27; no. 5; pp. 1578 - 1581
• Main Authors: Toczek, Jakub, Wu, Jing, Hillmer, Ansel T., Han, Jinah, Esterlis, Irina, Cosgrove, Kelly P., Liu, Chi, Sadeghi, Mehran M.
• Format: Journal Article
• Language: English
• Published: Cham Elsevier Inc 01.10.2020; Springer International Publishing; Springer Nature B.V; Springer Verlag
• Subjects: Adult; Aorta - diagnostic imaging; Aorta - metabolism; Brief Report; Cardiology; FDG; Fluorodeoxyglucose F18 - pharmacokinetics; Humans; Image analysis; Imaging; Inflammation; Life Sciences; Medicine; Medicine & Public Health; Middle Aged; Nuclear Medicine; PET; Positron-Emission Tomography; Radiology; Radiopharmaceuticals - pharmacokinetics; Reproducibility of Results; Vascular imaging; CT; Image analysis; SUV; TBR; FDG; Inflammation; PET; Vascular imaging
• ISSN: 1071-3581; 1532-6551
• DOI: 10.1007/s12350-020-02055-x

2-deoxy-2- [18F] fluoro-d-glucose (FDG) PET is commonly used for the assessment of vessel wall inflammation. Guidelines for analysis of arterial wall FDG signal recommend the use of the average of maximal standardized uptake value (mean SUVmax) and target-to-blood (mean TBRmax) ratio. However, these...