Abnormal Neurofilament Transport Caused by Targeted Disruption of Neuronal Kinesin Heavy Chain KIF5A
To test the hypothesis that fast anterograde molecular motor proteins power the slow axonal transport of neurofilaments (NFs), we used homologous recombination to generate mice lacking the neuronal-specific conventional kinesin heavy chain, KIF5A. Because null KIF5A mutants die immediately after bir...
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Published in | The Journal of cell biology Vol. 161; no. 1; pp. 55 - 66 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Rockefeller University Press
14.04.2003
The Rockefeller University Press |
Subjects | |
Online Access | Get full text |
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