Stem Cell Therapy for Spinal Cord Injury

• Published in: Cell transplantation Vol. 30; p. 963689721989266
• Main Authors: Huang, Liyi, Fu, Chenying, Xiong, Feng, He, Chengqi, Wei, Quan
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 2021; Sage Publications Ltd; SAGE Publishing
• Subjects: Animals; Bone marrow; Cell therapy; Clinical trials; Dystonia; Embryo cells; Extracellular vesicles; Humans; Immunomodulation; Mesenchyme; Neural stem cells; Neural Stem Cells - transplantation; Paraplegia; Pluripotency; Progenitor cells; Regeneration; Review; Spinal cord injuries; Spinal Cord Injuries - therapy; Stem cells; spinal cord injury; stem cells; NSCs; iPSCs; EVs; U-MSCs; BM-MSCs; NPCs; AD-MSCs; ESCs

Traumatic spinal cord injury (SCI) results in direct and indirect damage to neural tissues, which results in motor and sensory dysfunction, dystonia, and pathological reflex that ultimately lead to paraplegia or tetraplegia. A loss of cells, axon regeneration failure, and time-sensitive pathophysiol...