Serum SARS-COV-2 Nucleocapsid Protein: A Sensitivity and Specificity Early Diagnostic Marker for SARS-COV-2 Infection

• Published in: Frontiers in cellular and infection microbiology Vol. 10; p. 470
• Main Authors: Li, Tao, Wang, Li, Wang, Huihui, Li, Xuemei, Zhang, Shubing, Xu, Yuanhong, Wei, Wei
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 04.09.2020
• Subjects: Antibodies, Viral - blood; Betacoronavirus - isolation & purification; Biomarkers - blood; Cellular and Infection Microbiology; Clinical Laboratory Techniques - methods; colloidal gold immunochromatography; Coronavirus Infections - blood; Coronavirus Infections - diagnosis; Coronavirus Nucleocapsid Proteins; COVID-19; COVID-19 Testing; diagnostic value; Enzyme-Linked Immunosorbent Assay - methods; Female; Humans; Male; nucleocapsid protein; Nucleocapsid Proteins - blood; Pandemics; Phosphoproteins; Pneumonia, Viral - blood; Pneumonia, Viral - diagnosis; Pregnancy; SARS-CoV-2; Sensitivity and Specificity; COVID-19; colloidal gold immunochromatography; nucleocapsid protein; SARS-CoV-2; diagnostic value

To explore the diagnostic value of serum severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein assay in the early stages of SARS-COV-2 infection. Serum N protein level in SARS-COV-2 infected patients and non-SARS-COV-2 infected population was measured by enzyme-linked...