Importance of sodium-glucose cotransporter 2 inhibitor use in diabetic patients with acute heart failure

• Published in: Therapeutic advances in cardiovascular disease Vol. 13; p. 1753944719894509
• Main Authors: Kambara, Takahiro, Shibata, Rei, Osanai, Hiroyuki, Nakashima, Yoshihito, Asano, Hiroshi, Murohara, Toyoaki, Ajioka, Masayoshi
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 2019; SAGE PUBLICATIONS, INC; SAGE Publishing
• Subjects: Acute Disease; Acute Kidney Injury - epidemiology; Acute Kidney Injury - prevention & control; Aged; Aged, 80 and over; Biomarkers - blood; Blood Glucose - drug effects; Blood Glucose - metabolism; Comorbidity; Diabetes; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - diagnosis; Diabetes Mellitus, Type 2 - drug therapy; Diabetes Mellitus, Type 2 - epidemiology; Diuretics; Female; Glycated Hemoglobin A - metabolism; Heart failure; Heart Failure - diagnosis; Heart Failure - drug therapy; Heart Failure - epidemiology; Heart Failure - physiopathology; Humans; Japan - epidemiology; Male; Middle Aged; Original Research; Patient Admission; Progression-Free Survival; Recovery of Function; Retrospective Studies; Risk Factors; Sodium Potassium Chloride Symporter Inhibitors - administration & dosage; Sodium Potassium Chloride Symporter Inhibitors - adverse effects; Sodium-Glucose Transporter 2 Inhibitors - administration & dosage; Sodium-Glucose Transporter 2 Inhibitors - adverse effects; Time Factors; Japan; heart failure; acute kidney injury; diabetes mellitus; SGLT2 inhibitor

Background: It is known that once heart failure occurs in older patients with diabetes, the overall prognosis is extremely poor. We investigated whether early initiation of SGLT2 inhibitor therapy after admission was beneficial for diabetic patients requiring inpatient treatment for acute heart fail...