Synthesis, Characterization, and Antibacterial Activities of Novel Sulfonamides Derived through Condensation of Amino Group Containing Drugs, Amino Acids, and Their Analogs

• Published in: BioMed research international Vol. 2015; no. 2015; pp. 1 - 7
• Main Authors: Abdul Qadir, Muhammad, Iqbal, Muhammad, Ahmed, Mahmood
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2015; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Amines - chemistry; Amino acids; Amino Acids - chemistry; Anti-Bacterial Agents - chemical synthesis; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Antibacterial agents; Bacteria; Bacteria - drug effects; Chemical properties; Chemistry; Colleges & universities; Condensation; Drugs; E coli; Escherichia coli; Health aspects; Klebsiella pneumoniae; Membrane filters; Microbial Sensitivity Tests; Pharmaceutical Preparations - chemistry; Physiological aspects; Properties; Staphylococcus aureus; Sulfonamides; Sulfonamides - chemical synthesis; Sulfonamides - chemistry; Sulfonamides - pharmacology; Lahore Pakistan

Novel sulfonamides were developed and structures of the new products were confirmed by elemental and spectral analysis (FT-IR, ESI-MS, 1HNMR, and 13CNMR). In vitro, developed compounds were screened for their antibacterial activities against medically important gram (+) and gram (−) bacterial strain...