Application prospective of nanoprobes with MRI and FI dual-modality imaging on breast cancer stem cells in tumor

• Published in: Journal of nanobiotechnology Vol. 14; no. 1; p. 52
• Main Authors: Chen, Hetao, Wang, Yu, Wang, Tong, Shi, Dongxing, Sun, Zengrong, Xia, Chunhui, Wang, Baiqi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 23.06.2016; BioMed Central
• Subjects: Animals; Antigens, Neoplasm - genetics; Antigens, Neoplasm - metabolism; Biomarkers, Tumor - genetics; Biomarkers, Tumor - metabolism; Breast cancer; Breast Neoplasms - diagnosis; Breast Neoplasms - genetics; Breast Neoplasms - pathology; Contrast Media - chemistry; Contrast Media - metabolism; Contrast Media - pharmacokinetics; Diagnosis; Female; Gadolinium DTPA - chemistry; Gadolinium DTPA - metabolism; Gadolinium DTPA - pharmacokinetics; Humans; Immunoconjugates - chemistry; Immunoconjugates - metabolism; Immunoconjugates - pharmacokinetics; Ki-67 Antigen - genetics; Ki-67 Antigen - metabolism; Magnetic resonance imaging; Magnetic Resonance Imaging - instrumentation; Magnetic Resonance Imaging - methods; Methods; Mice; Nanoparticles; Nanoparticles - chemistry; Nanoparticles - metabolism; Neoplastic Stem Cells - metabolism; Neoplastic Stem Cells - pathology; Neoplastic Stem Cells - ultrastructure; Optical Imaging - instrumentation; Optical Imaging - methods; Optical properties; Quantum Dots - chemistry; Quantum Dots - metabolism; Receptor, ErbB-2 - genetics; Receptor, ErbB-2 - metabolism; Review; China; Fluorescence; Breast cancer; Cancer stem cells; Imaging; Magnetic resonance

Breast cancer (BC) is a serious disease to threat lives of women. Numerous studies have proved that BC originates from cancer stem cells (CSCs). But at present, no one approach can quickly and simply identify breast cancer stem cells (BCSCs) in solid tumor. Nanotechnology is probably able to realize...