Systematic CT Methodology for the Evaluation of Subclinical Leaflet Thrombosis

• Published in: JACC. Cardiovascular imaging Vol. 10; no. 4; pp. 461 - 470
• Main Authors: Jilaihawi, Hasan, Asch, Federico M., Manasse, Eric, Ruiz, Carlos E., Jelnin, Vladimir, Kashif, Mohammad, Kawamori, Hiroyuki, Maeno, Yoshio, Kazuno, Yoshio, Takahashi, Nobuyuki, Olson, Richard, Alkhatib, Joe, Berman, Daniel, Friedman, John, Gellada, Norman, Chakravarty, Tarun, Makkar, Raj R.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2017
• Subjects: aortic stenosis; Aortic Valve - diagnostic imaging; Aortic Valve - physiopathology; Aortic Valve - surgery; aortic valve replacement; Asymptomatic Diseases; Bioprosthesis; Cardiovascular; Echocardiography, Transesophageal; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation - adverse effects; Heart Valve Prosthesis Implantation - instrumentation; Humans; leaflet thrombosis; Predictive Value of Tests; Risk Factors; Severity of Illness Index; TAVI; TAVR; Thrombosis - diagnostic imaging; Thrombosis - etiology; Thrombosis - therapy; Tomography, X-Ray Computed; transcatheter aortic valve implantation; transcatheter aortic valve replacement; Transcatheter Aortic Valve Replacement - adverse effects; Transcatheter Aortic Valve Replacement - instrumentation; Treatment Outcome; transcatheter aortic valve implantation; HALT; aortic valve replacement; TAVI; HU; TAVR; MPR; CT; AS; RELM; aortic stenosis; HAM; TEE; leaflet thrombosis; transcatheter aortic valve replacement; SOV; VR; hypoattenuated leaflet thickening; volume rendered; hypoattenuation affecting motion; computed tomography; Hounsfield unit; sinus of Valsalva; multiplanar reconstruction; reduced leaflet motion; transesophageal echocardiography

Subclinical leaflet thrombosis was recently described in a randomized trial of transcatheter aortic valve replacement. It was subsequently demonstrated in a series of registries that this was a commonly observed imaging finding seen in all transcatheter and surgical bioprostheses. The phenomenon has...