Analysis of hyperalgesia time courses in humans after painful electrical high-frequency stimulation identifies a possible transition from early to late LTP-like pain plasticity - Pfau, Doreen B.; Klein, Thomas; Putzer, Daniel; Pogatzki-Zahn, Esther M.; Treede, Rolf-Detlef; Magerl, Walter (Pain (Amsterdam), 2011)
Keywords: Adult; Biological and medical sciences; Biophysical Phenomena; Central sensitization; Chronic pain; Early LTP; Electric Stimulation - adverse effects; Female; Fundamental and applied biological sciences. Psychology; Humans; Hyperalgesia - physiopathology; Illness and personality; Illness, stress and coping; Late LTP; Likelihood Functions; Long-term potentiation; Long-Term Potentiation - physiology; LTP; LTP1; LTP2; Male; Pain Measurement; Pain Threshold - physiology; Persistent pain; Psychology and medicine; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Secondary hyperalgesia; Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors; Statistics as Topic; Time Factors; Vertebrates: nervous system and sense organs; Young Adult; Secondary hyperalgesia; Early LTP; Long-term potentiation; Central sensitization; Late LTP; LTP; LTP2; LTP1; Persistent pain; Chronic pain; Allodynia; Human; Potentiation; Sensation; Electrical stimulus; Recovery; Electrodes; Pain; Synaptic plasticity; Skin; Sensitization; High frequency; Time analysis