Consistent Regional Heterogeneity of Passive Diastolic Stretch and Systolic Deformation in the Healthy Heart: Age-Related Changes in Left Ventricle Contractility

The consistency of the normal spatial distribution of segmental passive stretch (PreS) and systolic strain (SS) within the left ventricle was investigated and a recently proposed echocardiographic estimate of left ventricular (LV) contractility was used to detect contractility changes with age. Here...

Full description

Saved in:
Bibliographic Details
Published inUltrasound in medicine & biology Vol. 40; no. 1; pp. 37 - 44
Main Authors Jasaityte, Ruta, D'hooge, Jan, Herbots, Lieven, Daraban, Ana M., Rademakers, Frank, Claus, Piet
Format Journal Article
LanguageEnglish
Published England Elsevier Inc 01.01.2014
Subjects
Online AccessGet full text

Cover

Loading…
Abstract The consistency of the normal spatial distribution of segmental passive stretch (PreS) and systolic strain (SS) within the left ventricle was investigated and a recently proposed echocardiographic estimate of left ventricular (LV) contractility was used to detect contractility changes with age. Hereto, in 54 healthy subjects, segmental PreS and SS were measured on tissue Doppler images of six left ventricle walls. For each subject, a linear regression line was estimated through the segmental PreS and SS values. The slopes and intercepts of this PreS-SS relationship did not differ between age groups, suggesting no changes in LV contractility with age. Moreover, a consistent regional distribution of PreS was observed, with the highest values measured in the septum, resulting in a similar distribution of SS as a direct consequence of the Frank-Starling mechanism.
AbstractList The consistency of the normal spatial distribution of segmental passive stretch (PreS) and systolic strain (SS) within the left ventricle was investigated and a recently proposed echocardiographic estimate of left ventricular (LV) contractility was used to detect contractility changes with age. Hereto, in 54 healthy subjects, segmental PreS and SS were measured on tissue Doppler images of six left ventricle walls. For each subject, a linear regression line was estimated through the segmental PreS and SS values. The slopes and intercepts of this PreS-SS relationship did not differ between age groups, suggesting no changes in LV contractility with age. Moreover, a consistent regional distribution of PreS was observed, with the highest values measured in the septum, resulting in a similar distribution of SS as a direct consequence of the Frank-Starling mechanism.The consistency of the normal spatial distribution of segmental passive stretch (PreS) and systolic strain (SS) within the left ventricle was investigated and a recently proposed echocardiographic estimate of left ventricular (LV) contractility was used to detect contractility changes with age. Hereto, in 54 healthy subjects, segmental PreS and SS were measured on tissue Doppler images of six left ventricle walls. For each subject, a linear regression line was estimated through the segmental PreS and SS values. The slopes and intercepts of this PreS-SS relationship did not differ between age groups, suggesting no changes in LV contractility with age. Moreover, a consistent regional distribution of PreS was observed, with the highest values measured in the septum, resulting in a similar distribution of SS as a direct consequence of the Frank-Starling mechanism.
The consistency of the normal spatial distribution of segmental passive stretch (PreS) and systolic strain (SS) within the left ventricle was investigated and a recently proposed echocardiographic estimate of left ventricular (LV) contractility was used to detect contractility changes with age. Hereto, in 54 healthy subjects, segmental PreS and SS were measured on tissue Doppler images of six left ventricle walls. For each subject, a linear regression line was estimated through the segmental PreS and SS values. The slopes and intercepts of this PreS-SS relationship did not differ between age groups, suggesting no changes in LV contractility with age. Moreover, a consistent regional distribution of PreS was observed, with the highest values measured in the septum, resulting in a similar distribution of SS as a direct consequence of the Frank-Starling mechanism.
Abstract The consistency of the normal spatial distribution of segmental passive stretch (PreS) and systolic strain (SS) within the left ventricle was investigated and a recently proposed echocardiographic estimate of left ventricular (LV) contractility was used to detect contractility changes with age. Hereto, in 54 healthy subjects, segmental PreS and SS were measured on tissue Doppler images of six left ventricle walls. For each subject, a linear regression line was estimated through the segmental PreS and SS values. The slopes and intercepts of this PreS-SS relationship did not differ between age groups, suggesting no changes in LV contractility with age. Moreover, a consistent regional distribution of PreS was observed, with the highest values measured in the septum, resulting in a similar distribution of SS as a direct consequence of the Frank-Starling mechanism.
Author D'hooge, Jan
Claus, Piet
Rademakers, Frank
Jasaityte, Ruta
Daraban, Ana M.
Herbots, Lieven
Author_xml – sequence: 1
  givenname: Ruta
  surname: Jasaityte
  fullname: Jasaityte, Ruta
  email: ruta.jasaityte@uzleuven.be
  organization: Division of Cardiovascular Imaging and Dynamics, Department of Cardiovascular Sciences, Catholic University of Leuven, Leuven, Belgium
– sequence: 2
  givenname: Jan
  surname: D'hooge
  fullname: D'hooge, Jan
  organization: Division of Cardiovascular Imaging and Dynamics, Department of Cardiovascular Sciences, Catholic University of Leuven, Leuven, Belgium
– sequence: 3
  givenname: Lieven
  surname: Herbots
  fullname: Herbots, Lieven
  organization: Heart Center Hasselt, Jessa Hospital, Hasselt, Belgium
– sequence: 4
  givenname: Ana M.
  surname: Daraban
  fullname: Daraban, Ana M.
  organization: Division of Cardiovascular Imaging and Dynamics, Department of Cardiovascular Sciences, Catholic University of Leuven, Leuven, Belgium
– sequence: 5
  givenname: Frank
  surname: Rademakers
  fullname: Rademakers, Frank
  organization: Division of Cardiovascular Imaging and Dynamics, Department of Cardiovascular Sciences, Catholic University of Leuven, Leuven, Belgium
– sequence: 6
  givenname: Piet
  surname: Claus
  fullname: Claus, Piet
  organization: Division of Cardiovascular Imaging and Dynamics, Department of Cardiovascular Sciences, Catholic University of Leuven, Leuven, Belgium
BackLink https://www.ncbi.nlm.nih.gov/pubmed/24239364$$D View this record in MEDLINE/PubMed
BookMark eNqNksFuEzEQhi1URNPCKyCLE5cNtnfXu9sDoiSUIkUCNYC4WY53nDg4drGdSnkc3rRekkqoEiIXj2X98814_jlDJ847QOgVJWNKKH-zHm9tCjJuoF8YP2aElmPSjQmpn6ARbZuuYB39cYJGpCS0qDnrTtFZjGtCSMPL5hk6ZRUru5JXI_R74l00MYFL-AaWxjtp8TUkCH4JDkzaYa_xFxmjuQM8NTImb43C8xQgqRWWrsfz3eFxCtqHjUyZgo3DaQUZJW1a7YYY0gW-XEJxA1Ym6PFkJd0S4qCcgU74e-4hGGUB557y_1QyNtd_jp5qaSO8OMRz9O3qw9fJdTH7_PHT5HJWqJo1qdBaVR2tVKf7UlPgAA3htJaqZQvJda1YvgJVfdNy1uaz1woqyYFrJuu6Ls_R6z33NvhfW4hJbExUYK104LdR0JrypiKct_-XVryqupaRQfryIN0usl_iNpiNDDvx4EAWvNsLVPAxBtBCmfRnhHkExgpKxGC6WIu_TReD6YJ0IpueERePEA9Vjkqe7pMhz_bOQBBRGXAKehNAJdF7cxzm7SOMssYZJe1P2EFc-23Im5VHIyITRMyH1Rw2k5aEdG1TZsD7fwOO7eIechL_lQ
CitedBy_id crossref_primary_10_1016_j_athoracsur_2015_04_025
crossref_primary_10_1371_journal_pone_0158302
crossref_primary_10_1371_journal_pone_0228027
crossref_primary_10_1109_TMI_2015_2479556
crossref_primary_10_1371_journal_pone_0173383
Cites_doi 10.1152/ajpheart.00568.2011
10.1186/1532-429X-14-70
10.1152/ajpheart.00610.2004
10.1161/01.CIR.71.5.994
10.1136/hrt.45.3.248
10.1016/S0002-8703(03)00248-5
10.1093/eurheartj/ehn280
10.1161/01.CIR.86.2.504
10.1016/S0895-7061(03)00846-X
10.1093/ejechocard/jep188
10.1016/S0025-6196(12)61059-3
10.1073/pnas.0601533103
10.1016/j.echo.2003.10.001
10.1002/mrm.10543
10.1016/j.jcmg.2012.10.022
10.1152/ajpheart.2001.280.2.H610
10.1161/CIRCULATIONAHA.112.111302
10.1161/01.CIR.74.5.991
10.1016/j.jbiomech.2010.02.022
10.1136/hrt.74.2.186
ContentType Journal Article
Copyright 2014 World Federation for Ultrasound in Medicine & Biology
World Federation for Ultrasound in Medicine & Biology
Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.
Copyright_xml – notice: 2014 World Federation for Ultrasound in Medicine & Biology
– notice: World Federation for Ultrasound in Medicine & Biology
– notice: Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
7QO
8FD
FR3
P64
DOI 10.1016/j.ultrasmedbio.2013.09.005
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
Biotechnology Research Abstracts
Technology Research Database
Engineering Research Database
Biotechnology and BioEngineering Abstracts
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
Engineering Research Database
Biotechnology Research Abstracts
Technology Research Database
Biotechnology and BioEngineering Abstracts
DatabaseTitleList MEDLINE - Academic


MEDLINE

Engineering Research Database
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Biology
Physics
EISSN 1879-291X
EndPage 44
ExternalDocumentID 24239364
10_1016_j_ultrasmedbio_2013_09_005
S0301562913009873
1_s2_0_S0301562913009873
Genre Journal Article
GroupedDBID ---
--K
-DZ
.1-
.55
.FO
.GJ
0R~
123
1B1
1P~
1RT
1~5
29Q
3O-
4.4
457
4G.
53G
5RE
5VS
7-5
AAEDT
AAEDW
AALRI
AAQFI
AAQXK
AAWTL
AAXUO
AAYWO
ABDPE
ABJNI
ABLJU
ABMAC
ABNEU
ABOCM
ABWVN
ACGFS
ACIUM
ACRPL
ACVFH
ADBBV
ADCNI
ADMUD
ADNMO
AENEX
AEUPX
AEVXI
AFJKZ
AFPUW
AFRHN
AFTJW
AGCQF
AGQPQ
AHHHB
AIGII
AITUG
AJUYK
AKRWK
ALMA_UNASSIGNED_HOLDINGS
AMRAJ
APXCP
ASPBG
AVWKF
AZFZN
BELOY
C5W
CS3
DU5
EBS
EFJIC
EFKBS
EJD
F5P
FDB
FEDTE
FGOYB
FIRID
G-2
GBLVA
HEI
HMK
HMO
HVGLF
HZ~
IHE
J1W
K-O
KOM
L7B
M29
M41
MO0
NQ-
O9-
OI~
OU0
P2P
R2-
ROL
RPZ
SAE
SDG
SEL
SES
SEW
SSZ
WUQ
X7M
XH2
Z5R
ZGI
ZXP
ZY4
~S-
AACTN
ABTAH
ADPAM
AFCTW
RIG
AAIAV
AGZHU
AHPSJ
ALXNB
G8K
ZA5
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
7QO
8FD
FR3
P64
ID FETCH-LOGICAL-c527t-ffc4914c9fd3f1e6ee70615ac82ba6f5c2ac8e1cd78628d78dfce4a6e6f2a5553
ISSN 0301-5629
1879-291X
IngestDate Fri Jul 11 15:41:41 EDT 2025
Fri Jul 11 10:47:46 EDT 2025
Mon Jul 21 05:42:26 EDT 2025
Tue Jul 01 04:13:43 EDT 2025
Thu Apr 24 23:04:49 EDT 2025
Fri Feb 23 02:29:13 EST 2024
Sun Feb 23 10:19:15 EST 2025
Tue Aug 26 16:41:09 EDT 2025
IsPeerReviewed true
IsScholarly true
Issue 1
Keywords Passive diastolic left ventricular stretch
Myocardial deformation imaging
Left ventricular strain
Contractility
Language English
License https://www.elsevier.com/tdm/userlicense/1.0
Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.
LinkModel OpenURL
MergedId FETCHMERGED-LOGICAL-c527t-ffc4914c9fd3f1e6ee70615ac82ba6f5c2ac8e1cd78628d78dfce4a6e6f2a5553
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ObjectType-Article-2
ObjectType-Feature-1
PMID 24239364
PQID 1464498208
PQPubID 23479
PageCount 8
ParticipantIDs proquest_miscellaneous_1516740668
proquest_miscellaneous_1464498208
pubmed_primary_24239364
crossref_citationtrail_10_1016_j_ultrasmedbio_2013_09_005
crossref_primary_10_1016_j_ultrasmedbio_2013_09_005
elsevier_sciencedirect_doi_10_1016_j_ultrasmedbio_2013_09_005
elsevier_clinicalkeyesjournals_1_s2_0_S0301562913009873
elsevier_clinicalkey_doi_10_1016_j_ultrasmedbio_2013_09_005
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate January 2014
2014
2014-1-00
2014-Jan
20140101
PublicationDateYYYYMMDD 2014-01-01
PublicationDate_xml – month: 01
  year: 2014
  text: January 2014
PublicationDecade 2010
PublicationPlace England
PublicationPlace_xml – name: England
PublicationTitle Ultrasound in medicine & biology
PublicationTitleAlternate Ultrasound Med Biol
PublicationYear 2014
Publisher Elsevier Inc
Publisher_xml – name: Elsevier Inc
References Zwanenburg, Gotte, Kuijer, Hofman, Knaapen, Heethaar, van Rossum, Marcus (bib21) 2005; 288
Klein, Burstow, Tajik, Zachariah, Bailey, Seward (bib10) 1994; 69
Galema, Geleijnse, Yap, van Domburg, Biagini, Vletter, Ten Cate (bib6) 2008; 9
Naito, Arisawa, Harada, Yamagami, Kozuka, Tamura (bib14) 1995; 74
Ramanathan, Jia, Ghanem, Ryu, Rudy (bib16) 2006; 103
Glower, Spratt, Snow, Kabas, Davis, Olsen, Tyson, Sabiston, Rankin (bib7) 1985; 71
McGowan, Cleland (bib12) 2003; 146
Choi, D'hooge, Rademakers, Claus (bib2) 2010; 43
Ennis, Epstein, Kellman, Fananapazir, McVeigh, Arai (bib4) 2003; 50
Fujimoto, Borlaug, Lewis, Hastings, Shafer, Bhella, Carrick-Ranson, Levine (bib5) 2013; 127
Jasaityte, Claus, Teske, Herbots, Verheyden, Jurcut, Rademakers, D'hooge (bib9) 2013; 6
Kuznetsova, Herbots, Richart, D'hooge, Thijs, Fagard, Herregods, Staessen (bib11) 2008; 29
Stratton, Cerqueira, Schwartz, Levy, Veith, Kahn, Abrass (bib18) 1992; 86
Pasipoularides, Mirsky, Hess, Grimm, Krayenbuehl (bib15) 1986; 74
Sun, Popovic, Greenberg, Xu, Asher, Stewart, Thomas (bib19) 2004; 17
Greenbaum, Ho, Gibson, Becker, Anderson (bib8) 1981; 45
Thorstensen, Dalen, Amundsen, Aase, Stoylen (bib20) 2010; 11
Salmasi, Alimo, Jepson, Dancy (bib17) 2003; 16
Mekkaoui, Huang, Chen, Dai, Reese, Kostis, Thiagalingam, Maurovich-Horvat, Ruskin, Hoffmann, Jackowski, Sosnovik (bib13) 2012; 14
Bogaert, Rademakers (bib1) 2001; 280
Choi, Rademakers, Claus (bib3) 2011; 301
Galema (10.1016/j.ultrasmedbio.2013.09.005_bib6) 2008; 9
Ramanathan (10.1016/j.ultrasmedbio.2013.09.005_bib16) 2006; 103
Thorstensen (10.1016/j.ultrasmedbio.2013.09.005_bib20) 2010; 11
Mekkaoui (10.1016/j.ultrasmedbio.2013.09.005_bib13) 2012; 14
Ennis (10.1016/j.ultrasmedbio.2013.09.005_bib4) 2003; 50
Naito (10.1016/j.ultrasmedbio.2013.09.005_bib14) 1995; 74
Fujimoto (10.1016/j.ultrasmedbio.2013.09.005_bib5) 2013; 127
Choi (10.1016/j.ultrasmedbio.2013.09.005_bib2) 2010; 43
Glower (10.1016/j.ultrasmedbio.2013.09.005_bib7) 1985; 71
Jasaityte (10.1016/j.ultrasmedbio.2013.09.005_bib9) 2013; 6
Klein (10.1016/j.ultrasmedbio.2013.09.005_bib10) 1994; 69
Bogaert (10.1016/j.ultrasmedbio.2013.09.005_bib1) 2001; 280
Stratton (10.1016/j.ultrasmedbio.2013.09.005_bib18) 1992; 86
Choi (10.1016/j.ultrasmedbio.2013.09.005_bib3) 2011; 301
Kuznetsova (10.1016/j.ultrasmedbio.2013.09.005_bib11) 2008; 29
Pasipoularides (10.1016/j.ultrasmedbio.2013.09.005_bib15) 1986; 74
Greenbaum (10.1016/j.ultrasmedbio.2013.09.005_bib8) 1981; 45
McGowan (10.1016/j.ultrasmedbio.2013.09.005_bib12) 2003; 146
Zwanenburg (10.1016/j.ultrasmedbio.2013.09.005_bib21) 2005; 288
Sun (10.1016/j.ultrasmedbio.2013.09.005_bib19) 2004; 17
Salmasi (10.1016/j.ultrasmedbio.2013.09.005_bib17) 2003; 16
References_xml – volume: 74
  start-page: 991
  year: 1986
  end-page: 1001
  ident: bib15
  article-title: Myocardial relaxation and passive diastolic properties in man
  publication-title: Circulation
– volume: 127
  start-page: 55
  year: 2013
  end-page: 62
  ident: bib5
  article-title: Hemodynamic responses to rapid saline loading: The impact of age, sex, and heart failure
  publication-title: Circulation
– volume: 11
  start-page: 149
  year: 2010
  end-page: 156
  ident: bib20
  article-title: Reproducibility in echocardiographic assessment of the left ventricular global and regional function, the HUNT study
  publication-title: Eur J Echocardiogr
– volume: 6
  start-page: 419
  year: 2013
  end-page: 428
  ident: bib9
  article-title: The slope of the segmental stretch-strain relationship as a noninvasive index of LV inotropy
  publication-title: JACC Cardiovasc Imaging
– volume: 74
  start-page: 186
  year: 1995
  end-page: 191
  ident: bib14
  article-title: Assessment of right ventricular regional contraction and comparison with the left ventricle in normal humans: A cine magnetic resonance study with presaturation myocardial tagging
  publication-title: Br Heart J
– volume: 71
  start-page: 994
  year: 1985
  end-page: 1009
  ident: bib7
  article-title: Linearity of the Frank-Starling relationship in the intact heart: The concept of preload recruitable stroke work
  publication-title: Circulation
– volume: 280
  start-page: H610
  year: 2001
  end-page: H620
  ident: bib1
  article-title: Regional nonuniformity of normal adult human left ventricle
  publication-title: Am J Physiol Heart Circ Physiol
– volume: 86
  start-page: 504
  year: 1992
  end-page: 512
  ident: bib18
  article-title: Differences in cardiovascular responses to isoproterenol in relation to age and exercise training in healthy men
  publication-title: Circulation
– volume: 50
  start-page: 638
  year: 2003
  end-page: 642
  ident: bib4
  article-title: Assessment of regional systolic and diastolic dysfunction in familial hypertrophic cardiomyopathy using MR tagging
  publication-title: Magn Reson Med
– volume: 14
  start-page: 70
  year: 2012
  ident: bib13
  article-title: Fiber architecture in remodeled myocardium revealed with a quantitative diffusion CMR tractography framework and histological validation
  publication-title: J Cardiovasc Magn Reson
– volume: 288
  start-page: H787
  year: 2005
  end-page: H794
  ident: bib21
  article-title: Regional timing of myocardial shortening is related to prestretch from atrial contraction: Assessment by high temporal resolution MRI tagging in humans
  publication-title: Am J Physiol Heart Circ Physiol
– volume: 146
  start-page: 388
  year: 2003
  end-page: 397
  ident: bib12
  article-title: Reliability of reporting left ventricular systolic function by echocardiography: A systematic review of 3 methods
  publication-title: Am Heart J
– volume: 301
  start-page: H2351
  year: 2011
  end-page: H2361
  ident: bib3
  article-title: Left-ventricular shape determines intramyocardial mechanical heterogeneity
  publication-title: Am J Physiol Heart Circ Physiol
– volume: 17
  start-page: 132
  year: 2004
  end-page: 138
  ident: bib19
  article-title: Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging
  publication-title: J Am Soc Echocardiogr
– volume: 43
  start-page: 1745
  year: 2010
  end-page: 1753
  ident: bib2
  article-title: Influence of left-ventricular shape on passive filling properties and end-diastolic fiber stress and strain
  publication-title: J Biomech
– volume: 16
  start-page: 473
  year: 2003
  end-page: 477
  ident: bib17
  article-title: Age-associated changes in left ventricular diastolic function are related to increasing left ventricular mass
  publication-title: Am J Hypertens
– volume: 45
  start-page: 248
  year: 1981
  end-page: 263
  ident: bib8
  article-title: Left ventricular fibre architecture in man
  publication-title: Br Heart J
– volume: 29
  start-page: 2014
  year: 2008
  end-page: 2023
  ident: bib11
  article-title: Left ventricular strain and strain rate in a general population
  publication-title: Eur Heart J
– volume: 9
  start-page: 250
  year: 2008
  end-page: 254
  ident: bib6
  article-title: Assessment of left ventricular ejection fraction after myocardial infarction using contrast echocardiography
  publication-title: Eur J Echocardiogr
– volume: 103
  start-page: 6309
  year: 2006
  end-page: 6314
  ident: bib16
  article-title: Activation and repolarization of the normal human heart under complete physiological conditions
  publication-title: Proc Natl Acad Sci USA
– volume: 69
  start-page: 212
  year: 1994
  end-page: 224
  ident: bib10
  article-title: Effects of age on left ventricular dimensions and filling dynamics in 117 normal persons
  publication-title: Mayo Clin Proc
– volume: 301
  start-page: H2351
  year: 2011
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib3
  article-title: Left-ventricular shape determines intramyocardial mechanical heterogeneity
  publication-title: Am J Physiol Heart Circ Physiol
  doi: 10.1152/ajpheart.00568.2011
– volume: 14
  start-page: 70
  year: 2012
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib13
  article-title: Fiber architecture in remodeled myocardium revealed with a quantitative diffusion CMR tractography framework and histological validation
  publication-title: J Cardiovasc Magn Reson
  doi: 10.1186/1532-429X-14-70
– volume: 288
  start-page: H787
  year: 2005
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib21
  article-title: Regional timing of myocardial shortening is related to prestretch from atrial contraction: Assessment by high temporal resolution MRI tagging in humans
  publication-title: Am J Physiol Heart Circ Physiol
  doi: 10.1152/ajpheart.00610.2004
– volume: 71
  start-page: 994
  year: 1985
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib7
  article-title: Linearity of the Frank-Starling relationship in the intact heart: The concept of preload recruitable stroke work
  publication-title: Circulation
  doi: 10.1161/01.CIR.71.5.994
– volume: 9
  start-page: 250
  year: 2008
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib6
  article-title: Assessment of left ventricular ejection fraction after myocardial infarction using contrast echocardiography
  publication-title: Eur J Echocardiogr
– volume: 45
  start-page: 248
  year: 1981
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib8
  article-title: Left ventricular fibre architecture in man
  publication-title: Br Heart J
  doi: 10.1136/hrt.45.3.248
– volume: 146
  start-page: 388
  year: 2003
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib12
  article-title: Reliability of reporting left ventricular systolic function by echocardiography: A systematic review of 3 methods
  publication-title: Am Heart J
  doi: 10.1016/S0002-8703(03)00248-5
– volume: 29
  start-page: 2014
  year: 2008
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib11
  article-title: Left ventricular strain and strain rate in a general population
  publication-title: Eur Heart J
  doi: 10.1093/eurheartj/ehn280
– volume: 86
  start-page: 504
  year: 1992
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib18
  article-title: Differences in cardiovascular responses to isoproterenol in relation to age and exercise training in healthy men
  publication-title: Circulation
  doi: 10.1161/01.CIR.86.2.504
– volume: 16
  start-page: 473
  year: 2003
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib17
  article-title: Age-associated changes in left ventricular diastolic function are related to increasing left ventricular mass
  publication-title: Am J Hypertens
  doi: 10.1016/S0895-7061(03)00846-X
– volume: 11
  start-page: 149
  year: 2010
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib20
  article-title: Reproducibility in echocardiographic assessment of the left ventricular global and regional function, the HUNT study
  publication-title: Eur J Echocardiogr
  doi: 10.1093/ejechocard/jep188
– volume: 69
  start-page: 212
  year: 1994
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib10
  article-title: Effects of age on left ventricular dimensions and filling dynamics in 117 normal persons
  publication-title: Mayo Clin Proc
  doi: 10.1016/S0025-6196(12)61059-3
– volume: 103
  start-page: 6309
  year: 2006
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib16
  article-title: Activation and repolarization of the normal human heart under complete physiological conditions
  publication-title: Proc Natl Acad Sci USA
  doi: 10.1073/pnas.0601533103
– volume: 17
  start-page: 132
  year: 2004
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib19
  article-title: Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging
  publication-title: J Am Soc Echocardiogr
  doi: 10.1016/j.echo.2003.10.001
– volume: 50
  start-page: 638
  year: 2003
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib4
  article-title: Assessment of regional systolic and diastolic dysfunction in familial hypertrophic cardiomyopathy using MR tagging
  publication-title: Magn Reson Med
  doi: 10.1002/mrm.10543
– volume: 6
  start-page: 419
  year: 2013
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib9
  article-title: The slope of the segmental stretch-strain relationship as a noninvasive index of LV inotropy
  publication-title: JACC Cardiovasc Imaging
  doi: 10.1016/j.jcmg.2012.10.022
– volume: 280
  start-page: H610
  year: 2001
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib1
  article-title: Regional nonuniformity of normal adult human left ventricle
  publication-title: Am J Physiol Heart Circ Physiol
  doi: 10.1152/ajpheart.2001.280.2.H610
– volume: 127
  start-page: 55
  year: 2013
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib5
  article-title: Hemodynamic responses to rapid saline loading: The impact of age, sex, and heart failure
  publication-title: Circulation
  doi: 10.1161/CIRCULATIONAHA.112.111302
– volume: 74
  start-page: 991
  year: 1986
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib15
  article-title: Myocardial relaxation and passive diastolic properties in man
  publication-title: Circulation
  doi: 10.1161/01.CIR.74.5.991
– volume: 43
  start-page: 1745
  year: 2010
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib2
  article-title: Influence of left-ventricular shape on passive filling properties and end-diastolic fiber stress and strain
  publication-title: J Biomech
  doi: 10.1016/j.jbiomech.2010.02.022
– volume: 74
  start-page: 186
  year: 1995
  ident: 10.1016/j.ultrasmedbio.2013.09.005_bib14
  article-title: Assessment of right ventricular regional contraction and comparison with the left ventricle in normal humans: A cine magnetic resonance study with presaturation myocardial tagging
  publication-title: Br Heart J
  doi: 10.1136/hrt.74.2.186
SSID ssj0007637
Score 2.0950143
Snippet The consistency of the normal spatial distribution of segmental passive stretch (PreS) and systolic strain (SS) within the left ventricle was investigated and...
Abstract The consistency of the normal spatial distribution of segmental passive stretch (PreS) and systolic strain (SS) within the left ventricle was...
SourceID proquest
pubmed
crossref
elsevier
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 37
SubjectTerms Adult
Aged
Aging - physiology
Contractility
Diastole - physiology
Echocardiography, Doppler - methods
Elastic Modulus - physiology
Elasticity Imaging Techniques - methods
Heart Ventricles - diagnostic imaging
Humans
Image Interpretation, Computer-Assisted - methods
Left ventricular strain
Middle Aged
Myocardial Contraction - physiology
Myocardial deformation imaging
Passive diastolic left ventricular stretch
Radiology
Reference Values
Reproducibility of Results
Sensitivity and Specificity
Stress, Mechanical
Systole - physiology
Tensile Strength - physiology
Ventricular Function, Left - physiology
Title Consistent Regional Heterogeneity of Passive Diastolic Stretch and Systolic Deformation in the Healthy Heart: Age-Related Changes in Left Ventricle Contractility
URI https://www.clinicalkey.com/#!/content/1-s2.0-S0301562913009873
https://www.clinicalkey.es/playcontent/1-s2.0-S0301562913009873
https://dx.doi.org/10.1016/j.ultrasmedbio.2013.09.005
https://www.ncbi.nlm.nih.gov/pubmed/24239364
https://www.proquest.com/docview/1464498208
https://www.proquest.com/docview/1516740668
Volume 40
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LbxMxELZCKhAXBAVKeMlIcEIb7fsB4lDaQlVahKCperO8Xm9pVe2i7uYQ_g3_jR_CjB-bDW1Q6MVZWZ7E3vliz4znQchLN0mKMIoiJ8hk4YSCp7APSu7wqBBl4uVuWGI08sHneHcS7h1Hx4PB757X0rTNx-LnlXEl1-Eq9AFfMUr2PzjbfSl0wDPwF1rgMLQr8VhV2wQ2VehafGIzBcObqoFEGmeLLyAeK_egUw6CHua0xptoYJb22pyZzm3ZxTFa30cdojTDzwttQTyRjvKeQ7OwCktQ3rT7smxfH6GZGCeIQYStir1CCb8v_E7Oob_BOk5IZW_1FfhMLqjOn4c3HIh16b6v07Y7O7Zf-cn3utb14PfmyN4FdNRto60MmJSqZ4HnOTd5Erix_Rorh44rtXFdrueAlJb192yd4mkBm3oD1hlkzFGuM0teOiS0veJsPFWrhtXCGtHJL1AZb91ofjRad4CdrU-e0_hj1_mG08HZ4DVgluoyLH9l7PZY4zOXXRp6g6z5oMz4Q7L28f3-0WYnMcAen-jbLr1SmxxX-SEum-UyQWqZoqQEpsO75I7RdOimhu09MpDVOrmpa5_O1smtA8N_6FRuyKK5T37NEU0toukComldUoNo2iGaGkRTQDS1iKY9RNPTigKiqUE0VYh-Q3t4pgbPOBLxTDs80wU8PyCTDzuHW7uOKSLiiMhPWqcsRZh5ocjKIig9GUuZoBTPRernPC4j4cOj9ESRgG6fQluUQoY8lnHpc9jEgodkWNWVfESokAFP84wXEY9DLxE887jwXO4lsoSjTI5IZjnChMmwj4Vezpl1pTxjfW4y5CZzMwbcHJGgo_2h88ysRPXWMp7ZSGo4-xkgfSXq5Cpq2ZgtrmHLkDwi7zpKI6lrCXzlX35hUcrgOMM7Sl7JetqgJSIMM1BL0n-MiTB0CnQlGLOhId69M1QPsyAOH197bU_IbdyAtJn1KRm2F1P5DBSPNn9u_rd_AJthNg0
linkProvider Elsevier
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Consistent+Regional+Heterogeneity+of+Passive+Diastolic+Stretch+and+Systolic+Deformation+in+the+Healthy+Heart%3A+Age-Related+Changes+in+Left+Ventricle+Contractility&rft.jtitle=Ultrasound+in+medicine+%26+biology&rft.au=Jasaityte%2C+Ruta&rft.au=D%27hooge%2C+Jan&rft.au=Herbots%2C+Lieven&rft.au=Daraban%2C+Ana+M&rft.date=2014&rft.issn=0301-5629&rft.volume=40&rft.issue=1&rft.spage=37&rft.epage=44&rft_id=info:doi/10.1016%2Fj.ultrasmedbio.2013.09.005&rft.externalDBID=ECK1-s2.0-S0301562913009873&rft.externalDocID=1_s2_0_S0301562913009873
thumbnail_m http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F03015629%2FS0301562912X00231%2Fcov150h.gif