Performance comparison of immunodiffusion, enzyme-linked immunosorbent assay, immunochromatography and hemagglutination for serodiagnosis of human pythiosis

• Published in: Diagnostic microbiology and infectious disease Vol. 76; no. 1; pp. 42 - 45
• Main Authors: Chareonsirisuthigul, Takol, Khositnithikul, Rommanee, Intaramat, Akarin, Inkomlue, Ruchuros, Sriwanichrak, Kanchana, Piromsontikorn, Savittree, Kitiwanwanich, Sureewan, Lowhnoo, Tassanee, Yingyong, Wanta, Chaiprasert, Angkana, Banyong, Ramrada, Ratanabanangkoon, Kavi, Brandhorst, Tristan T., Krajaejun, Theerapong
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2013
• Subjects: antibodies; Antibodies, Fungal - blood; Antigens, Fungal - blood; debridement; Diagnosis; ELISA; enzyme-linked immunosorbent assay; Enzyme-Linked Immunosorbent Assay - methods; Hemagglutination; Humans; immunoaffinity chromatography; Immunochromatography; Immunochromatography - methods; Immunodiffusion; Immunodiffusion - methods; Infectious Disease; infectious diseases; Internal Medicine; morbidity; mortality; patients; Pythiosis; Pythiosis - diagnosis; Pythiosis - microbiology; Pythium - immunology; Pythium - isolation & purification; Pythium insidiosum; Sensitivity and Specificity; serodiagnosis; Serologic Tests - methods; Hemagglutination; Diagnosis; Immunochromatography; Pythiosis; Immunodiffusion; ELISA

Pythiosis is a life-threatening infectious disease caused by the fungus-like organism Pythium insidiosum. Morbidity and mortality rates of pythiosis are high. The treatment of choice for pythiosis is surgical debridement of infected tissue. Early and accurate diagnosis is critical for effective trea...