Tenascin-C promotes the repair of cartilage defects in mice

• Published in: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association Vol. 25; no. 2; pp. 324 - 330
• Main Authors: Unno, Hironori, Hasegawa, Masahiro, Suzuki, Yoshiaki, Iino, Takahiro, Imanaka-Yoshida, Kyoko, Yoshida, Toshimichi, Sudo, Akihiro
• Format: Journal Article
• Language: English
• Published: Japan Elsevier B.V 01.03.2020

The effects of tenascin-C (TNC) on cartilage repair were examined in cartilage defect model mice. An in vitro study was also performed to determine the mechanism of cartilage repair with TNC. Full-thickness osteochondral defects were filled with TNC (group A: 100 μg/ml, group B: 10 μg/ml, group C: e...