Instruction of myeloid cells by the tumor microenvironment: Open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations

• Published in: Oncoimmunology Vol. 1; no. 7; pp. 1135 - 1145
• Main Authors: Schouppe, Elio, De Baetselier, Patrick, Van Ginderachter, Jo A., Sarukhan, Adelaida
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.10.2012; Landes Bioscience
• Subjects: Binding; Biology; Bioscience; Calcium; Cancer; Cell; Cycle; ER stress; exosomes; hypoxia; Landes; myeloid cell plasticity; myeloid cells; myeloid-derived suppressor cells; Organogenesis; Proteins; Review; tumor-associated dendritic cells; tumor-associated macrophages; tumor-associated neutrophils

The versatility and plasticity of myeloid cell polarization/differentiation has turned out to be crucial in health and disease, and has become the subject of intense investigation during the last years. On one hand, myeloid cells provide a critical contribution to tissue homeostasis and repair. On t...