Successful Treatment with Adalimumab for Intestinal Behcet's Disease during Pregnancy

• Published in: Internal Medicine Vol. 55; no. 10; pp. 1375 - 1378
• Main Authors: Fujikawa, Keita, Endo, Yushiro, Mizokami, Akinari, Takahashi, Kosuke, Tabuchi, Maiko, Ohba, Kazuo, Nakamura, Hideki, Kawakami, Atsushi
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01.01.2016
• Subjects: adalimumab; Adalimumab - therapeutic use; Adult; Anti-Inflammatory Agents - therapeutic use; Antibodies, Monoclonal - therapeutic use; Behcet Syndrome - complications; Behcet Syndrome - drug therapy; Duodenal Ulcer - etiology; Female; Humans; intestinal Behcet's disease; placental transition; Pregnancy; Pregnancy Complications - drug therapy; Treatment Outcome

A 36-year-old Japanese woman with intestinal Behcet's disease was admitted to our hospital due to a recurrent ileocecal ulcer. Because infliximab (IFX) showed secondary failure, IFX was switched to adalimumab (ADA). After the third injection of ADA, she was unexpectedly 4-weeks pregnant. ADA wa...