Improvement in d-xylose utilization and isobutanol production in S. cerevisiae by adaptive laboratory evolution and rational engineering

• Published in: Journal of industrial microbiology & biotechnology Vol. 47; no. 6-7; pp. 497 - 510
• Main Authors: Promdonkoy, Peerada, Mhuantong, Wuttichai, Champreda, Verawat, Tanapongpipat, Sutipa, Runguphan, Weerawat
• Format: Journal Article
• Language: English
• Published: Cham Oxford University Press 01.07.2020; Springer International Publishing
• Subjects: Biochemistry; Biodiesel fuels; Biofuels; Bioinformatics; Biomass; Biomedical and Life Sciences; Biotechnology; Butanols - chemistry; Climate change; Climate effects; Diesel engines; Engineering; Evolution; feedstocks; Fermentation; Fossil fuels; Gasoline; Genetic Engineering; Genome, Fungal; Genomes; Greenhouse effect; Greenhouse gases; greenhouses; Growth rate; Industrial Microbiology; Inorganic Chemistry; Isobutanol; Jet engine fuels; Laboratories; Life Sciences; Metabolic Engineering; Metabolic Engineering and Synthetic Biology - Original Paper; Metabolism; Microbiology; Microorganisms; Mutation; Nucleotides; Plasmids - metabolism; Reverse engineering; Saccharomyces cerevisiae; Saccharomyces cerevisiae - metabolism; sequence analysis; specific growth rate; Strains (organisms); Sugar; transportation; Utilization; Xylose; Xylose - metabolism; Yeast; yeasts; Isobutanol production; Yeast; Xylose utilization; Biofuels; Adaptive laboratory evolution

Abstract As the effects of climate change become apparent, metabolic engineers and synthetic biologists are exploring sustainable sources for transportation fuels. The design and engineering of microorganisms to produce gasoline, diesel, and jet fuel compounds from renewable feedstocks can significa...