Screening for Astragalus hamosus Triterpenoid Saponins Using HPTLC Methods: Prior Identification of Azukisaponin Isomers

Due to their particular structural characteristics, the extraction and isolation of saponins from plants present a serious challenge. In this study, specific extraction protocols were first implemented to extract the secondary metabolites from and, more precisely, the saponins. Subsequent purificati...

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Published inMolecules (Basel, Switzerland) Vol. 27; no. 17; p. 5376
Main Authors Nafti, Khouloud, Giacinti, Geraldine, Marghali, Sonia, Raynaud, Christine Delgado
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 23.08.2022
MDPI
Subjects
Alzheimer's disease
Astragalus hamosus
Astragalus Plant - chemistry
azukisaponin
Biological activity
Breast cancer
Chromatography
Chromatography, Thin Layer - methods
Development systems
HPTLC
Isomers
Life Sciences
Metabolites
Plant Extracts - chemistry
Polarity
Purification
Saponins
Saponins - chemistry
Secondary metabolites
Seeds
Solvents
soyasaponin
Thin layer chromatography
Triterpenes - chemistry
triterpenoid saponin
azukisaponin
triterpenoid saponin
Astragalus hamosus
soyasaponin
HPTLC
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Abstract Due to their particular structural characteristics, the extraction and isolation of saponins from plants present a serious challenge. In this study, specific extraction protocols were first implemented to extract the secondary metabolites from and, more precisely, the saponins. Subsequent purification of the extracts was based on a single chromatographic technique, high-performance thin-layer chromatography, applying two development systems: a one-step system that separated molecules according to their polarity and a multiple development system that made it possible to detect the triterpenoid saponins, azukisaponin or soyasapogenol at a retarded Rf of 0.2. The difficulties of detecting the saponins encountered during the extraction and purification of the extracts have been highlighted and the strategy carried out to isolate the saponins has been discussed.
AbstractList Due to their particular structural characteristics, the extraction and isolation of saponins from plants present a serious challenge. In this study, specific extraction protocols were first implemented to extract the secondary metabolites from Astragalus hamosus and, more precisely, the saponins. Subsequent purification of the extracts was based on a single chromatographic technique, high-performance thin-layer chromatography, applying two development systems: a one-step system that separated molecules according to their polarity and a multiple development system that made it possible to detect the triterpenoid saponins, azukisaponin or soyasapogenol at a retarded Rf of 0.2. The difficulties of detecting the Astragalus hamosus saponins encountered during the extraction and purification of the extracts have been highlighted and the strategy carried out to isolate the saponins has been discussed.Due to their particular structural characteristics, the extraction and isolation of saponins from plants present a serious challenge. In this study, specific extraction protocols were first implemented to extract the secondary metabolites from Astragalus hamosus and, more precisely, the saponins. Subsequent purification of the extracts was based on a single chromatographic technique, high-performance thin-layer chromatography, applying two development systems: a one-step system that separated molecules according to their polarity and a multiple development system that made it possible to detect the triterpenoid saponins, azukisaponin or soyasapogenol at a retarded Rf of 0.2. The difficulties of detecting the Astragalus hamosus saponins encountered during the extraction and purification of the extracts have been highlighted and the strategy carried out to isolate the saponins has been discussed.
Due to their particular structural characteristics, the extraction and isolation of saponins from plants present a serious challenge. In this study, specific extraction protocols were first implemented to extract the secondary metabolites from Astragalus hamosus and, more precisely, the saponins. Subsequent purification of the extracts was based on a single chromatographic technique, high-performance thin-layer chromatography, applying two development systems: a one-step system that separated molecules according to their polarity and a multiple development system that made it possible to detect the triterpenoid saponins, azukisaponin or soyasapogenol at a retarded Rf of 0.2. The difficulties of detecting the Astragalus hamosus saponins encountered during the extraction and purification of the extracts have been highlighted and the strategy carried out to isolate the saponins has been discussed
Due to their particular structural characteristics, the extraction and isolation of saponins from plants present a serious challenge. In this study, specific extraction protocols were first implemented to extract the secondary metabolites from Astragalus hamosus and, more precisely, the saponins. Subsequent purification of the extracts was based on a single chromatographic technique, high-performance thin-layer chromatography, applying two development systems: a one-step system that separated molecules according to their polarity and a multiple development system that made it possible to detect the triterpenoid saponins, azukisaponin or soyasapogenol at a retarded Rf of 0.2. The difficulties of detecting the Astragalus hamosus saponins encountered during the extraction and purification of the extracts have been highlighted and the strategy carried out to isolate the saponins has been discussed.
Due to their particular structural characteristics, the extraction and isolation of saponins from plants present a serious challenge. In this study, specific extraction protocols were first implemented to extract the secondary metabolites from and, more precisely, the saponins. Subsequent purification of the extracts was based on a single chromatographic technique, high-performance thin-layer chromatography, applying two development systems: a one-step system that separated molecules according to their polarity and a multiple development system that made it possible to detect the triterpenoid saponins, azukisaponin or soyasapogenol at a retarded Rf of 0.2. The difficulties of detecting the saponins encountered during the extraction and purification of the extracts have been highlighted and the strategy carried out to isolate the saponins has been discussed.
Due to their particular structural characteristics, the extraction and isolation of saponins from plants present a serious challenge. In this study, specific extraction protocols were first implemented to extract the secondary metabolites from Astragalus hamosus and, more precisely, the saponins. Subsequent purification of the extracts was based on a single chromatographic technique, high-performance thin-layer chromatography, applying two development systems: a one-step system that separated molecules according to their polarity and a multiple development system that made it possible to detect the triterpenoid saponins, azukisaponin or soyasapogenol at a retarded Rf of 0.2. The difficulties of detecting the Astragalus hamosus saponins encountered during the extraction and purification of the extracts have been highlighted and the strategy carried out to isolate the saponins has been discussed.
Author Raynaud, Christine Delgado
Marghali, Sonia
Giacinti, Geraldine
Nafti, Khouloud
AuthorAffiliation 1 Laboratoire de Chimie Ago-Industrielle (LCA), Université de Toulouse, INRAe, 4 Allée Emile Monso, 31030 Toulouse, France
3 Centre d’Application et de Traitement des Agro-Ressources (CATAR), Toulouse-INP, ENSIACET, 4 Allée Emile Monso, 31030 Toulouse, France
2 Laboratoire de Génétique Moléculaire, Immunologie et Biotechnologie, Faculté des Sciences de Tunis, Université de Tunis El Manar, Tunis 1068, Tunisia
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Cites_doi 10.1016/j.phytochem.2011.01.015
10.3390/molecules24071416
10.1080/13880200390501370
10.20944/preprints201611.0128.v1
10.1021/jf0202279
10.1016/j.chroma.2006.01.037
10.1556/JPC.26.2013.3.8
10.1016/S0147-9571(99)00020-X
10.1016/j.jep.2021.114067
10.3390/catal8100479
10.3390/molecules26175251
10.1007/BF02274471
10.1016/j.foodchem.2009.06.066
10.3390/separations5030039
10.3390/molecules26175373
10.1016/j.ifset.2010.06.004
10.1016/j.chroma.2016.12.056
10.1023/B:EUPH.0000003881.85977.10
10.1021/jf0482663
10.1007/s10298-010-0603-4
10.1139/apnm-2017-0585
10.1016/j.dib.2017.03.055
10.1016/j.fitote.2010.06.004
10.1111/1750-3841.15398
10.1093/chromsci/bmx062
10.1007/978-1-61779-624-1
10.1016/j.jep.2004.05.016
10.1080/10408390600698197
10.3897/pharmacia.68.e60621
10.1016/j.foodres.2014.01.057
10.1007/s13205-019-1846-x
10.1016/j.phytol.2015.01.014
10.1039/c1np00015b
10.3390/molecules26247705
10.1055/s-2002-35654
10.1016/j.jcs.2013.02.002
10.3390/separations9070163
10.1016/j.jep.2011.01.039
10.1016/j.jfca.2020.103568
10.1039/C8SM01815D
10.1016/j.intimp.2011.08.018
10.1016/j.ejps.2012.07.004
10.1016/S0021-9673(01)01556-4
10.1007/s11101-014-9347-3
10.1016/j.jasms.2006.02.013
10.31557/APJCP.2022.23.2.731
10.3390/molecules25133086
10.1016/j.foodchem.2008.07.053
10.1021/jf2018758
10.1080/12538078.2012.758496
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Keywords azukisaponin
triterpenoid saponin
Astragalus hamosus
soyasaponin
HPTLC
Language English
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References Cheok (ref_27) 2014; 59
(ref_1) 2015; 5
Li (ref_22) 2010; 11
Kambouche (ref_53) 2011; 9
Estrada (ref_23) 2000; 23
Ma (ref_52) 2002; 50
ref_13
Chan (ref_20) 2013; 57
Li (ref_32) 2020; 85
Rahmania (ref_35) 2012; 159
ref_51
Hassan (ref_15) 2010; 119
Gupta (ref_49) 2019; 9
Podolak (ref_50) 2013; 26
Huhman (ref_30) 2005; 53
Munier (ref_42) 1977; 10
Kaltbach (ref_57) 2020; 92
Milheiro (ref_39) 2017; 12
Waheed (ref_19) 2012; 47
Hakim (ref_3) 2010; 1
Oleszek (ref_45) 2002; 967
ref_28
Shawky (ref_34) 2017; 55
Calabrese (ref_38) 2018; 14
Pistelli (ref_55) 2003; 41
Dini (ref_21) 2009; 113
Mazza (ref_14) 2007; 47
Fu (ref_31) 2021; 274
ref_33
Shkondrov (ref_7) 2021; 68
Osbourn (ref_12) 2011; 28
Mad (ref_36) 2006; 17
Sparg (ref_11) 2004; 94
Hamedi (ref_8) 2016; 2
ref_37
Salleh (ref_41) 2001; 7
Maamria (ref_54) 2015; 11
Oleszek (ref_29) 2006; 1112
Ionkova (ref_9) 2014; 13
Augustin (ref_10) 2011; 72
ref_47
Mahmoodi (ref_6) 2022; 2
ref_46
ref_44
ref_43
ref_40
Sun (ref_16) 2011; 11
Dineva (ref_25) 2010; 1
Ncube (ref_58) 2011; 134
Zoghlami (ref_2) 2003; 134
Bahaeddin (ref_5) 2017; 43
Giacinti (ref_56) 2017; 1483
Man (ref_18) 2010; 81
ref_48
Verotta (ref_26) 2002; 68
Krasteva (ref_24) 2008; 4
Shojaii (ref_4) 2015; 14
Cheng (ref_17) 2011; 59
References_xml – volume: 72
  start-page: 435
  year: 2011
  ident: ref_10
  article-title: Molecular Activities, Biosynthesis and Evolution of Triterpenoid Saponins
  publication-title: Phytochemistry
  doi: 10.1016/j.phytochem.2011.01.015
  contributor:
    fullname: Augustin
– ident: ref_46
  doi: 10.3390/molecules24071416
– volume: 41
  start-page: 568
  year: 2003
  ident: ref_55
  article-title: Further Saponins and Flavonoids from Astragalus verrucosus Moris
  publication-title: Pharm. Biol.
  doi: 10.1080/13880200390501370
  contributor:
    fullname: Pistelli
– ident: ref_51
  doi: 10.20944/preprints201611.0128.v1
– volume: 50
  start-page: 4861
  year: 2002
  ident: ref_52
  article-title: Chemical Analysis of Radix Astragali (Huangqi) in China: A Comparison with Its Adulterants and Seasonal Variations
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf0202279
  contributor:
    fullname: Ma
– volume: 1112
  start-page: 78
  year: 2006
  ident: ref_29
  article-title: Chromatographic Determination of Plant Saponins—An Update (2002–2005)
  publication-title: J. Chromatogr. A
  doi: 10.1016/j.chroma.2006.01.037
  contributor:
    fullname: Oleszek
– volume: 26
  start-page: 248
  year: 2013
  ident: ref_50
  article-title: Quantification of Saponins in Different Plant Parts of Lysimachia L. Species by Validated HPTLC-Densitometric Method
  publication-title: JPC-J. Planar Chromatogr.-Mod. TLC
  doi: 10.1556/JPC.26.2013.3.8
  contributor:
    fullname: Podolak
– volume: 23
  start-page: 27
  year: 2000
  ident: ref_23
  article-title: Isolation and Evaluation of Immunological Adjuvant Activities of Saponins from Polygala senega L.
  publication-title: Comp. Immunol. Microbiol. Infect. Dis.
  doi: 10.1016/S0147-9571(99)00020-X
  contributor:
    fullname: Estrada
– volume: 274
  start-page: 114067
  year: 2021
  ident: ref_31
  article-title: Deciphering the Metabolic Profile and Pharmacological Mechanisms of Achyranthes bidentata Blume Saponins Using Ultra-Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Coupled with Network Pharmacology-Based Investigation
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/j.jep.2021.114067
  contributor:
    fullname: Fu
– ident: ref_40
  doi: 10.3390/catal8100479
– ident: ref_47
  doi: 10.3390/molecules26175251
– volume: 10
  start-page: 226
  year: 1977
  ident: ref_42
  article-title: Nouvelles méthodes de séparation et comportement des alcaloides en chromatographie en milieux tres polaires, neutres ou acides, sur gel de silice non modifié (1ère partie)
  publication-title: Chromatographia
  doi: 10.1007/BF02274471
  contributor:
    fullname: Munier
– volume: 119
  start-page: 600
  year: 2010
  ident: ref_15
  article-title: Haemolytic and Antimicrobial Activities of Saponin-Rich Extracts from Guar Meal
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2009.06.066
  contributor:
    fullname: Hassan
– ident: ref_37
  doi: 10.3390/separations5030039
– ident: ref_43
  doi: 10.3390/molecules26175373
– volume: 11
  start-page: 637
  year: 2010
  ident: ref_22
  article-title: Optimization of Microwave-Assisted Extraction of Triterpene Saponins from Defatted Residue of Yellow Horn (Xanthoceras sorbifolia Bunge.) Kernel and Evaluation of Its Antioxidant Activity
  publication-title: Innov. Food Sci. Emerg. Technol.
  doi: 10.1016/j.ifset.2010.06.004
  contributor:
    fullname: Li
– volume: 1483
  start-page: 8
  year: 2017
  ident: ref_56
  article-title: Evaluation and Prevention of the Negative Matrix Effect of Terpenoids on Pesticides in Apples Quantification by Gas Chromatography–Tandem Mass Spectrometry
  publication-title: J. Chromatogr. A
  doi: 10.1016/j.chroma.2016.12.056
  contributor:
    fullname: Giacinti
– volume: 134
  start-page: 137
  year: 2003
  ident: ref_2
  article-title: Morphological Variation in Astragalus hamosus L. and Coronilla scorpioides L. Populations of Tunisia
  publication-title: Euphytica
  doi: 10.1023/B:EUPH.0000003881.85977.10
  contributor:
    fullname: Zoghlami
– ident: ref_48
– volume: 53
  start-page: 1914
  year: 2005
  ident: ref_30
  article-title: Quantification of Saponins in Aerial and Subterranean Tissues of Medicago truncatula
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf0482663
  contributor:
    fullname: Huhman
– volume: 9
  start-page: 2
  year: 2011
  ident: ref_53
  article-title: Activité antihyperglycémiante d’un stérol β-sitoglucoside isolé de la plante Anabasis articulata (Forssk) Moq
  publication-title: Phytothérapie
  doi: 10.1007/s10298-010-0603-4
  contributor:
    fullname: Kambouche
– volume: 43
  start-page: 558
  year: 2017
  ident: ref_5
  article-title: Dietary Supplementation with Allium hirtifolium and/or Astragalus hamosus Improved memory and Reduced Neuro-Inflammation in the Rat Model of Alzheimer’s Disease
  publication-title: Appl. Physiol. Nutr. Metab.
  doi: 10.1139/apnm-2017-0585
  contributor:
    fullname: Bahaeddin
– volume: 1
  start-page: 281
  year: 2010
  ident: ref_25
  article-title: In Vitro Antineoplastic Activity of Some Cytoreductive Drugs versus New Compounds of Plant Origin
  publication-title: Int. J. Curr. Chem.
  contributor:
    fullname: Dineva
– volume: 12
  start-page: 188
  year: 2017
  ident: ref_39
  article-title: Data on Changes in Red Wine Phenolic Compounds, Headspace Aroma Compounds and Sensory Profile after Treatment of Red Wines with Activated Carbons with Different Physicochemical Characteristics
  publication-title: Data Brief
  doi: 10.1016/j.dib.2017.03.055
  contributor:
    fullname: Milheiro
– volume: 81
  start-page: 703
  year: 2010
  ident: ref_18
  article-title: Chemical Study and Medical Application of Saponins as Anti-Cancer Agents
  publication-title: Fitoterapia
  doi: 10.1016/j.fitote.2010.06.004
  contributor:
    fullname: Man
– volume: 5
  start-page: 321
  year: 2015
  ident: ref_1
  article-title: Chemical constituents and pharmacological effects of Astragalus hamosus and Astragalus tribuloides grown in iraq
  publication-title: Asian J. Pharm. Sci. Tech.
– volume: 85
  start-page: 3183
  year: 2020
  ident: ref_32
  article-title: Characterization of Astragaloside I-IV Based on the Separation of HPTLC from Pleurotus ostreatus Cultivated with Astragalus
  publication-title: J. Food Sci.
  doi: 10.1111/1750-3841.15398
  contributor:
    fullname: Li
– volume: 4
  start-page: 269
  year: 2008
  ident: ref_24
  article-title: Antiproliferative Effects of a Flavonoid and Saponins from Astragalus hamosus against Human Tumor Cell Lines
  publication-title: Pharmacogn. Mag.
  contributor:
    fullname: Krasteva
– volume: 55
  start-page: 1059
  year: 2017
  ident: ref_34
  article-title: Simultaneous Determination of Soyasaponins and Isoflavones in Soy (Glycine max L.) Products by HPTLC-Densitometry-Multiple Detection
  publication-title: J. Chromatogr. Sci.
  doi: 10.1093/chromsci/bmx062
  contributor:
    fullname: Shawky
– ident: ref_28
  doi: 10.1007/978-1-61779-624-1
– volume: 94
  start-page: 219
  year: 2004
  ident: ref_11
  article-title: Biological Activities and Distribution of Plant Saponins
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/j.jep.2004.05.016
  contributor:
    fullname: Sparg
– volume: 47
  start-page: 231
  year: 2007
  ident: ref_14
  article-title: Saponins: Properties, Applications and Processing
  publication-title: Crit. Rev. Food Sci. Nutr.
  doi: 10.1080/10408390600698197
  contributor:
    fullname: Mazza
– volume: 68
  start-page: 135
  year: 2021
  ident: ref_7
  article-title: Liquid Chromatography–High Resolution Mass Spectrometry Screening of Astragalus hamosus and Astragalus corniculatus
  publication-title: Pharmacia
  doi: 10.3897/pharmacia.68.e60621
  contributor:
    fullname: Shkondrov
– volume: 59
  start-page: 16
  year: 2014
  ident: ref_27
  article-title: Extraction and Quantification of Saponins: A Review
  publication-title: Food Res. Int.
  doi: 10.1016/j.foodres.2014.01.057
  contributor:
    fullname: Cheok
– volume: 9
  start-page: 311
  year: 2019
  ident: ref_49
  article-title: Qualitative HPTLC Phytochemical Profiling of Careya Arborea Roxb. Bark, Leaves and Seeds
  publication-title: 3 Biotech
  doi: 10.1007/s13205-019-1846-x
  contributor:
    fullname: Gupta
– volume: 1
  start-page: 34
  year: 2010
  ident: ref_3
  article-title: Evaluation of Anti-Inflammatory Activity of the Pods of Iklil-Ul-Malik (Astragalus hamosus Linn.)
  publication-title: Indian J. Nat. Prod. Ressour.
  contributor:
    fullname: Hakim
– volume: 11
  start-page: 286
  year: 2015
  ident: ref_54
  article-title: Cycloartane Glycosides from Astragalus gombo
  publication-title: Phytochem. Lett.
  doi: 10.1016/j.phytol.2015.01.014
  contributor:
    fullname: Maamria
– volume: 28
  start-page: 1261
  year: 2011
  ident: ref_12
  article-title: The Saponins: Polar Isoprenoids with Important and Diverse Biological Activities
  publication-title: Nat. Prod. Rep.
  doi: 10.1039/c1np00015b
  contributor:
    fullname: Osbourn
– ident: ref_13
  doi: 10.3390/molecules26247705
– volume: 68
  start-page: 986
  year: 2002
  ident: ref_26
  article-title: Cycloartane and Oleanane Saponins from Egyptian Astragalus spp. as Modulators of Lymphocyte Proliferation
  publication-title: Planta Med.
  doi: 10.1055/s-2002-35654
  contributor:
    fullname: Verotta
– volume: 57
  start-page: 480
  year: 2013
  ident: ref_20
  article-title: Isolation and Antioxidative Properties of Phenolics-Saponins Rich Fraction from Defatted Rice Bran
  publication-title: J. Cereal Sci.
  doi: 10.1016/j.jcs.2013.02.002
  contributor:
    fullname: Chan
– ident: ref_33
  doi: 10.3390/separations9070163
– volume: 134
  start-page: 775
  year: 2011
  ident: ref_58
  article-title: A Comparative Study of the Antimicrobial and Phytochemical Properties between Outdoor Grown and Micropropagated Tulbaghia violacea Harv. Plants
  publication-title: J. Ethnopharmacol.
  doi: 10.1016/j.jep.2011.01.039
  contributor:
    fullname: Ncube
– volume: 7
  start-page: 281
  year: 2001
  ident: ref_41
  article-title: Synthesis of Fatty Alkanolamides By Using Immobilized Lipases
  publication-title: Malays. J. Anal. Sci.
  contributor:
    fullname: Salleh
– volume: 92
  start-page: 103568
  year: 2020
  ident: ref_57
  article-title: New HPTLC Methods for Analysis of Major Bioactive Compounds in Mate (Ilex paraguariensis) Tea
  publication-title: J. Food Compos. Anal.
  doi: 10.1016/j.jfca.2020.103568
  contributor:
    fullname: Kaltbach
– volume: 14
  start-page: 9243
  year: 2018
  ident: ref_38
  article-title: Alcohol Induced Gelation of TEMPO-Oxidized Cellulose Nanofibril Dispersions
  publication-title: Soft Matter
  doi: 10.1039/C8SM01815D
  contributor:
    fullname: Calabrese
– volume: 11
  start-page: 2047
  year: 2011
  ident: ref_16
  article-title: Structure–Function Relationship of the Saponins from the Roots of Platycodon grandiflorum for Hemolytic and Adjuvant Activity
  publication-title: Int. Immunopharmacol.
  doi: 10.1016/j.intimp.2011.08.018
  contributor:
    fullname: Sun
– volume: 14
  start-page: 263
  year: 2015
  ident: ref_4
  article-title: Evaluation of Anti-Inflammatory and Analgesic Activity of the Extract and Fractions of Astragalus hamosus in Animal Models
  publication-title: Iran. J. Pharm. Res.
  contributor:
    fullname: Shojaii
– volume: 2
  start-page: 77
  year: 2016
  ident: ref_8
  article-title: Phytochemical Assessments of Astragalus hamosus Pods (Iklil-Ul-Malik)
  publication-title: Trends Pharm. Sci.
  contributor:
    fullname: Hamedi
– volume: 47
  start-page: 464
  year: 2012
  ident: ref_19
  article-title: A Novel Steroidal Saponin Glycoside from Fagonia indica Induces Cell-Selective Apoptosis or Necrosis in Cancer Cells
  publication-title: Eur. J. Pharm. Sci.
  doi: 10.1016/j.ejps.2012.07.004
  contributor:
    fullname: Waheed
– volume: 967
  start-page: 147
  year: 2002
  ident: ref_45
  article-title: Chromatographic Determination of Plant Saponins
  publication-title: J. Chromatogr. A
  doi: 10.1016/S0021-9673(01)01556-4
  contributor:
    fullname: Oleszek
– volume: 13
  start-page: 343
  year: 2014
  ident: ref_9
  article-title: Recent Progress in Phytochemistry, Pharmacology and Biotechnology of Astragalus Saponins
  publication-title: Phytochem. Rev.
  doi: 10.1007/s11101-014-9347-3
  contributor:
    fullname: Ionkova
– volume: 17
  start-page: 795
  year: 2006
  ident: ref_36
  article-title: Tandem Mass Spectrometric Analysis of a Complex Triterpene Saponin Mixture of Chenopodium quinoa
  publication-title: J. Am. Soc. Mass Spectrom.
  doi: 10.1016/j.jasms.2006.02.013
  contributor:
    fullname: Mad
– volume: 2
  start-page: 731
  year: 2022
  ident: ref_6
  article-title: Fabrication and Characterization of a Three-Dimensional Fibrin Gel Model to Evaluate Anti-Proliferative Effects of Astragalus hamosus Plant Extract on Breast Cancer Cells
  publication-title: Asian Pac. J. Cancer Prev.
  doi: 10.31557/APJCP.2022.23.2.731
  contributor:
    fullname: Mahmoodi
– ident: ref_44
  doi: 10.3390/molecules25133086
– volume: 113
  start-page: 411
  year: 2009
  ident: ref_21
  article-title: Saponins in Ipomoea Batatas Tubers: Isolation, Characterization, Quantification and Antioxidant Properties
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2008.07.053
  contributor:
    fullname: Dini
– volume: 59
  start-page: 11319
  year: 2011
  ident: ref_17
  article-title: Antiproliferation Effect and Apoptosis Mechanism of Prostate Cancer Cell PC-3 by Flavonoids and Saponins Prepared from Gynostemma pentaphyllum
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf2018758
  contributor:
    fullname: Cheng
– volume: 159
  start-page: 477
  year: 2012
  ident: ref_35
  article-title: Détection et Identification de Saponines Stéroïdes de Type Spirostane Chez Le Palmier Dattier Phœnix Dactylifera L. (Arecaceae)
  publication-title: Acta Bot. Gall.
  doi: 10.1080/12538078.2012.758496
  contributor:
    fullname: Rahmania
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Snippet Due to their particular structural characteristics, the extraction and isolation of saponins from plants present a serious challenge. In this study, specific...
SourceID doaj
pubmedcentral
hal
proquest
crossref
pubmed
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
StartPage 5376
SubjectTerms Alzheimer's disease
Astragalus hamosus
Astragalus Plant - chemistry
azukisaponin
Biological activity
Breast cancer
Chromatography
Chromatography, Thin Layer - methods
Development systems
HPTLC
Isomers
Life Sciences
Metabolites
Plant Extracts - chemistry
Polarity
Purification
Saponins
Saponins - chemistry
Secondary metabolites
Seeds
Solvents
soyasaponin
Thin layer chromatography
Triterpenes - chemistry
triterpenoid saponin
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Title Screening for Astragalus hamosus Triterpenoid Saponins Using HPTLC Methods: Prior Identification of Azukisaponin Isomers
URI https://www.ncbi.nlm.nih.gov/pubmed/36080144
https://www.proquest.com/docview/2711355116
https://www.proquest.com/docview/2712853919/abstract/
https://hal.inrae.fr/hal-03789437
https://pubmed.ncbi.nlm.nih.gov/PMC9457977
https://doaj.org/article/55ed617755c640e5a7b0e079241c91f9
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