CYP2C19 genetic polymorphism in the Vietnamese population

• Published in: Annals of Human Biology Vol. 46; no. 6; pp. 491 - 497
• Main Authors: Vu, Nhung Phuong, Nguyen, Hoa Thi Thanh, Tran, Ngoc Thi Bich, Nguyen, Ton Dang, Huynh, Hue Thi Thu, Nguyen, Xuan Thi, Nguyen, Duong Thuy, Nong, Hai Van, Nguyen, Ha Hai
• Format: Journal Article
• Language: English
• Published: England Taylor & Francis 18.08.2019; Informa UK Limited; Taylor & Francis Group
• Subjects: Alleles; Biology (General); Cytochrome P-450 CYP2C19 - genetics; Cytochrome P450; drug metabolism; Ethnic Groups; Human anatomy; Humans; personalised medicine; pharmacogenetics; Physiology; Polymerase Chain Reaction; polymorphism; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; QH301-705.5; QM1-695; QP1-981; Vietnam; Vietnam; personalised medicine; polymorphism; Cytochrome P450; pharmacogenetics; drug metabolism

Background: Genetic polymorphism of CYP2C19 has been shown to affect enzyme activity and thereby contribute to inter-individual variability in drug metabolism and response. The complete genetic variation of CYP2C19 in Vietnam still remains obscure even though data of common alleles in Vietnamese Kin...