Rapid Single-Step Immunochromatographic Assay for Angiostrongylus cantonensis Specific Antigen Detection

• Published in: Pathogens (Basel) Vol. 12; no. 6; p. 762
• Main Authors: Eamsobhana, Praphathip, Tungtrongchitr, Anchalee, Wanachiwanawin, Darawan, Boonyong, Sudarat, Yong, Hoi-Sen
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 25.05.2023; MDPI
• Subjects: 31-kDa antigen; active angiostrongyliasis; ambient temperature; Angiostrongylus; Angiostrongylus cantonensis; Antibodies; antigen detection; Antigens; blood serum; Cerebrospinal fluid; Chromatography; climate; Diagnostic systems; diagnostic techniques; etiology; Glycoproteins; Hospitals; immunoaffinity chromatography; Immunoassays; immunochromatographic test; Immunology; Infections; Laboratories; Laboratory tests; lateral flow assay; Leukocytes (eosinophilic); Meningitis; Meningoencephalitis; Parasites; Parasitic diseases; Parasitology; Parastrongylus cantonensis; Patients; point-of-care systems; Polyclonal antibodies; Pulmonary arteries; rapid methods; Reagents; Refrigeration; Room temperature; Temperature requirements; Tropical diseases; Thailand; Bangkok Thailand; 31-kDa antigen; active angiostrongyliasis; immunochromatographic test; antigen detection; lateral flow assay; Angiostrongylus cantonensis
• ISSN: 2076-0817; 2076-0817
• DOI: 10.3390/pathogens12060762

Angiostrongylus cantonensis is the major etiological nematode parasite causing eosinophilic meningitis and/or eosinophilic meningoencephalitis in humans. The rapid global spread of Angiostrongylus cantonensis and the emerging occurrence of the infection have exposed the shortcomings of traditional/c...