Whole genome sequencing revealed genetic diversity, population structure, and selective signature of Panou Tibetan sheep

• Published in: BMC genomics Vol. 24; no. 1; pp. 50 - 15
• Main Authors: Shi, Huibin, Li, Taotao, Su, Manchun, Wang, Huihui, Li, Qiao, Lang, Xia, Ma, Youji
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.01.2023; BioMed Central; BMC
• Subjects: Adaptation; Animal husbandry; Animals; Biological diversity; Breeding; Distribution; DNA sequencing; Domestic animals; Domestication; Fst and π ratio; Gene pool; Gene sequencing; Genes; Genetic aspects; Genetic diversity; Genetic resources; Genetic Variation; Genome; Genomes; Genomic analysis; Genomics; Heterozygosity; High altitude; Histone deacetylase; Homozygosity; Hypoxia; Indigenous species; Interferon-inducible protein; Kinases; Livestock; New varieties; Next-generation sequencing; Nucleotide sequencing; Panou Tibetan sheep; Phenotypic variations; Plant breeding; Polymorphism, Single Nucleotide; Population biology; Population differentiation; Population genetics; Population structure; Populations; Positive selection; Principal components analysis; Protein-tyrosine kinase; Proteins; Selection, Genetic; Sheep; Sheep - genetics; Sheep breeds; Software; Tibet; Tyrosine; Vesicular monoamine transporter; Whole Genome Sequencing; Zoological research; Tibet; China; Gansu China; United States > US; Fst and π ratio; Population structure; Panou Tibetan sheep; Positive selection

The detection of selective traits in different populations can not only reveal current mechanisms of artificial selection for breeding, but also provide new insights into phenotypic variation in new varieties and the search for genes associated with important traits. Panou sheep is a cultivated bree...