Effects of Helicobacter pylori Treatment on Incidence of Gastric Cancer in Older Individuals

• Published in: Gastroenterology (New York, N.Y. 1943) Vol. 155; no. 1; pp. 67 - 75
• Main Authors: Leung, Wai K., Wong, Irene O.L., Cheung, Ka Shing, Yeung, Kar Fu, Chan, Esther W., Wong, Angel Y.S., Chen, Lijia, Wong, Ian C.K., Graham, David Y.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2018
• Subjects: Adult; Aged; Amoxicillin - therapeutic use; Antacids - therapeutic use; Anti-Bacterial Agents - therapeutic use; Antibiotics; Bacteria; Bismuth - therapeutic use; Chemoprevention; Clarithromycin - therapeutic use; Drug Therapy, Combination; Female; Helicobacter Infections - drug therapy; Helicobacter Infections - epidemiology; Helicobacter pylori; Hong Kong - epidemiology; Humans; Incidence; Levofloxacin - therapeutic use; Male; Middle Aged; Protective Factors; Proton Pump Inhibitors - therapeutic use; Registries; Retrospective Studies; Risk Factors; Stomach Cancer; Stomach Neoplasms - epidemiology; Hong Kong; Stomach Cancer; CDARS; Antibiotics; Chemoprevention; CI; Bacteria; SIR

Although eradication of Helicobacter pylori infection reduces the risk of gastric cancer, few data are available on its effects in older subjects. We compared the age-specific risk of gastric cancer in a large cohort of subjects who received H pylori eradication therapy vs a matched general populati...