Inter-niche and inter-individual variation in gut microbial community assessment using stool, rectal swab, and mucosal samples

• Published in: Scientific reports Vol. 8; no. 1; pp. 4139 - 12
• Main Authors: Jones, Roshonda B., Zhu, Xiangzhu, Moan, Emili, Murff, Harvey J., Ness, Reid M., Seidner, Douglas L., Sun, Shan, Yu, Chang, Dai, Qi, Fodor, Anthony A., Azcarate-Peril, M. Andrea, Shrubsole, Martha J.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 07.03.2018; Nature Publishing Group
• Subjects: 45/23; 631/326/2565/2134; 692/4020/2741/2135; Adult; Aged; Aged, 80 and over; Bacteria; Bacteria - classification; Bacteria - genetics; Biopsy; Double-Blind Method; Epidemiology; Female; Gastrointestinal Microbiome - genetics; Genomes; Genotype & phenotype; Humanities and Social Sciences; Humans; Intestinal microflora; Intestinal Mucosa - microbiology; Male; Medicine; Metabolism; Metagenome; Microbial activity; Microbiomes; Microbiota; Middle Aged; Mucosa; multidisciplinary; Rectum; Sampling; Science; Science (multidisciplinary); Skin cancer; Transcription

The purpose of this study is to evaluate similarities and differences in gut bacterial measurements and stability in the microbial communities of three different types of samples that could be used to assess different niches of the gut microbiome: rectal swab, stool, and normal rectal mucosa samples...