Regular Use of Depot Medroxyprogesterone Acetate Causes Thinning of the Superficial Lining and Apical Distribution of Human Immunodeficiency Virus Target Cells in the Human Ectocervix - Edfeldt, Gabriella; Lajoie, Julie; Röhl, Maria; Oyugi, Julius; Åhlberg, Alexandra; Khalilzadeh-Binicy, Behnaz; Bradley, Frideborg; Mack, Matthias; Kimani, Joshua; Omollo, Kenneth; Wählby, Carolina; Fowke, Keith R; et al. (The Journal of infectious diseases, 2022)
Keywords: 17β-Estradiol; Acetic acid; CCR5 protein; CD4 antigen; Cervix Uteri - metabolism; Contraception; Contraceptive Agents, Female - adverse effects; digital image analysis; DMPA; E-cadherin; epithelial integrity; estradiol; Female; female genital mucosa; HIV; HIV Infections; HIV target cells; hormonal contraception; Human immunodeficiency virus; Humans; Image processing; Immune system; in situ staining; Localization; Major and Brief Reports; Medroxyprogesterone acetate; Medroxyprogesterone Acetate - adverse effects; Progesterone; Susceptibility; hormonal contraception; in situ staining; HIV; epithelial integrity; progesterone; HIV target cells; DMPA; female genital mucosa; digital image analysis; estradiol