A comparative assessment of human exposure to tetrabromobisphenol A and eight bisphenols including bisphenol A via indoor dust ingestion in twelve countries

Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and microenvironments) dust samples collected from 12 countries (China, Colombia, Greece, India, Japan, Kuwait, Pakistan, Romania, Saudi Arabia, South Korea, U...

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Published inEnvironment international Vol. 83; pp. 183 - 191
Main Authors Wang, Wei, Abualnaja, Khalid O., Asimakopoulos, Alexandros G., Covaci, Adrian, Gevao, Bondi, Johnson-Restrepo, Boris, Kumosani, Taha A., Malarvannan, Govindan, Minh, Tu Binh, Moon, Hyo-Bang, Nakata, Haruhiko, Sinha, Ravindra K., Kannan, Kurunthachalam
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.10.2015
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Abstract Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and microenvironments) dust samples collected from 12 countries (China, Colombia, Greece, India, Japan, Kuwait, Pakistan, Romania, Saudi Arabia, South Korea, U.S., and Vietnam). The concentrations of TBBPA and sum of eight bisphenols (ƩBPs) in dust samples ranged from <1 to 3600 and from 13 to 110,000ng/g, respectively. The highest TBBPA concentrations in house dust were found in samples from Japan (median: 140ng/g), followed by South Korea (84ng/g) and China (23ng/g). The highest ∑BPs concentrations were found in Greece (median: 3900ng/g), Japan (2600ng/g) and the U.S. (2200ng/g). Significant variations in BPA concentrations were found in dust samples collected from various microenvironments in offices and homes. Concentrations of TBBPA in house dust were significantly correlated with BPA and ∑BPs. Among the nine target chemicals analyzed, BPA was the predominant compound in dust from all countries. The proportion of TBBPA in sum concentrations of nine phenolic compounds analyzed in this study was the highest in dust samples from China (27%) and the lowest in Greece (0.41%). The median estimated daily intake (EDI) of ∑BPs through dust ingestion was the highest in Greece (1.6–17ng/kgbw/day), Japan (1.3–16) and the U.S. (0.89–9.6) for various age groups. Nevertheless, in comparison with the reported BPA exposure doses through diet, dust ingestion accounted for less than 10% of the total exposure doses in China and the U.S. For TBBPA, the EDI for infants and toddlers ranged from 0.01 to 3.4ng/kgbw/day, and dust ingestion is an important pathway for exposure accounting for 3.8–35% (median) of exposure doses in China. •TBBPA and bisphenols were measured in 388 indoor dust samples from 12 countries.•The contribution of house dust to daily intakes of TBBPA and BPA varied among countries.•Dust is an important source of TBBPA exposures in China, Japan and South Korea.•Dust ingestion accounted for 3.8–35% (median) of TBBPA exposure in China.•Contribution of dust to BPA intake is minor.
AbstractList Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and microenvironments) dust samples collected from 12 countries (China, Colombia, Greece, India, Japan, Kuwait, Pakistan, Romania, Saudi Arabia, South Korea, U.S., and Vietnam). The concentrations of TBBPA and sum of eight bisphenols (BPs) in dust samples ranged from <1 to 3600 and from 13 to 110,000ng/g, respectively. The highest TBBPA concentrations in house dust were found in samples from Japan (median: 140ng/g), followed by South Korea (84ng/g) and China (23ng/g). The highest capital sigma BPs concentrations were found in Greece (median: 3900ng/g), Japan (2600ng/g) and the U.S. (2200ng/g). Significant variations in BPA concentrations were found in dust samples collected from various microenvironments in offices and homes. Concentrations of TBBPA in house dust were significantly correlated with BPA and capital sigma BPs. Among the nine target chemicals analyzed, BPA was the predominant compound in dust from all countries. The proportion of TBBPA in sum concentrations of nine phenolic compounds analyzed in this study was the highest in dust samples from China (27%) and the lowest in Greece (0.41%). The median estimated daily intake (EDI) of capital sigma BPs through dust ingestion was the highest in Greece (1.6-17ng/kgbw/day), Japan (1.3-16) and the U.S. (0.89-9.6) for various age groups. Nevertheless, in comparison with the reported BPA exposure doses through diet, dust ingestion accounted for less than 10% of the total exposure doses in China and the U.S. For TBBPA, the EDI for infants and toddlers ranged from 0.01 to 3.4ng/kgbw/day, and dust ingestion is an important pathway for exposure accounting for 3.8-35% (median) of exposure doses in China.
Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and microenvironments) dust samples collected from 12 countries (China, Colombia, Greece, India, Japan, Kuwait, Pakistan, Romania, Saudi Arabia, South Korea, U.S., and Vietnam). The concentrations of TBBPA and sum of eight bisphenols (ƩBPs) in dust samples ranged from <1 to 3600 and from 13 to 110,000ng/g, respectively. The highest TBBPA concentrations in house dust were found in samples from Japan (median: 140ng/g), followed by South Korea (84ng/g) and China (23ng/g). The highest ∑BPs concentrations were found in Greece (median: 3900ng/g), Japan (2600ng/g) and the U.S. (2200ng/g). Significant variations in BPA concentrations were found in dust samples collected from various microenvironments in offices and homes. Concentrations of TBBPA in house dust were significantly correlated with BPA and ∑BPs. Among the nine target chemicals analyzed, BPA was the predominant compound in dust from all countries. The proportion of TBBPA in sum concentrations of nine phenolic compounds analyzed in this study was the highest in dust samples from China (27%) and the lowest in Greece (0.41%). The median estimated daily intake (EDI) of ∑BPs through dust ingestion was the highest in Greece (1.6–17ng/kgbw/day), Japan (1.3–16) and the U.S. (0.89–9.6) for various age groups. Nevertheless, in comparison with the reported BPA exposure doses through diet, dust ingestion accounted for less than 10% of the total exposure doses in China and the U.S. For TBBPA, the EDI for infants and toddlers ranged from 0.01 to 3.4ng/kgbw/day, and dust ingestion is an important pathway for exposure accounting for 3.8–35% (median) of exposure doses in China. •TBBPA and bisphenols were measured in 388 indoor dust samples from 12 countries.•The contribution of house dust to daily intakes of TBBPA and BPA varied among countries.•Dust is an important source of TBBPA exposures in China, Japan and South Korea.•Dust ingestion accounted for 3.8–35% (median) of TBBPA exposure in China.•Contribution of dust to BPA intake is minor.
Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and microenvironments) dust samples collected from 12 countries (China, Colombia, Greece, India, Japan, Kuwait, Pakistan, Romania, Saudi Arabia, South Korea, U.S., and Vietnam). The concentrations of TBBPA and sum of eight bisphenols (ƩBPs) in dust samples ranged from <1 to 3600 and from 13 to 110,000ng/g, respectively. The highest TBBPA concentrations in house dust were found in samples from Japan (median: 140ng/g), followed by South Korea (84ng/g) and China (23ng/g). The highest ∑BPs concentrations were found in Greece (median: 3900ng/g), Japan (2600ng/g) and the U.S. (2200ng/g). Significant variations in BPA concentrations were found in dust samples collected from various microenvironments in offices and homes. Concentrations of TBBPA in house dust were significantly correlated with BPA and ∑BPs. Among the nine target chemicals analyzed, BPA was the predominant compound in dust from all countries. The proportion of TBBPA in sum concentrations of nine phenolic compounds analyzed in this study was the highest in dust samples from China (27%) and the lowest in Greece (0.41%). The median estimated daily intake (EDI) of ∑BPs through dust ingestion was the highest in Greece (1.6–17ng/kgbw/day), Japan (1.3–16) and the U.S. (0.89–9.6) for various age groups. Nevertheless, in comparison with the reported BPA exposure doses through diet, dust ingestion accounted for less than 10% of the total exposure doses in China and the U.S. For TBBPA, the EDI for infants and toddlers ranged from 0.01 to 3.4ng/kgbw/day, and dust ingestion is an important pathway for exposure accounting for 3.8–35% (median) of exposure doses in China.
Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and microenvironments) dust samples collected from 12 countries (China, Colombia, Greece, India, Japan, Kuwait, Pakistan, Romania, Saudi Arabia, South Korea, U.S., and Vietnam). The concentrations of TBBPA and sum of eight bisphenols (ƩBPs) in dust samples ranged from <1 to 3600 and from 13 to 110,000 ng/g, respectively. The highest TBBPA concentrations in house dust were found in samples from Japan (median: 140 ng/g), followed by South Korea (84 ng/g) and China (23 ng/g). The highest ∑BPs concentrations were found in Greece (median: 3900 ng/g), Japan (2600 ng/g) and the U.S. (2200 ng/g). Significant variations in BPA concentrations were found in dust samples collected from various microenvironments in offices and homes. Concentrations of TBBPA in house dust were significantly correlated with BPA and ∑BPs. Among the nine target chemicals analyzed, BPA was the predominant compound in dust from all countries. The proportion of TBBPA in sum concentrations of nine phenolic compounds analyzed in this study was the highest in dust samples from China (27%) and the lowest in Greece (0.41%). The median estimated daily intake (EDI) of ∑BPs through dust ingestion was the highest in Greece (1.6-17 ng/kg bw/day), Japan (1.3-16) and the U.S. (0.89-9.6) for various age groups. Nevertheless, in comparison with the reported BPA exposure doses through diet, dust ingestion accounted for less than 10% of the total exposure doses in China and the U.S. For TBBPA, the EDI for infants and toddlers ranged from 0.01 to 3.4 ng/kg bw/day, and dust ingestion is an important pathway for exposure accounting for 3.8-35% (median) of exposure doses in China.Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and microenvironments) dust samples collected from 12 countries (China, Colombia, Greece, India, Japan, Kuwait, Pakistan, Romania, Saudi Arabia, South Korea, U.S., and Vietnam). The concentrations of TBBPA and sum of eight bisphenols (ƩBPs) in dust samples ranged from <1 to 3600 and from 13 to 110,000 ng/g, respectively. The highest TBBPA concentrations in house dust were found in samples from Japan (median: 140 ng/g), followed by South Korea (84 ng/g) and China (23 ng/g). The highest ∑BPs concentrations were found in Greece (median: 3900 ng/g), Japan (2600 ng/g) and the U.S. (2200 ng/g). Significant variations in BPA concentrations were found in dust samples collected from various microenvironments in offices and homes. Concentrations of TBBPA in house dust were significantly correlated with BPA and ∑BPs. Among the nine target chemicals analyzed, BPA was the predominant compound in dust from all countries. The proportion of TBBPA in sum concentrations of nine phenolic compounds analyzed in this study was the highest in dust samples from China (27%) and the lowest in Greece (0.41%). The median estimated daily intake (EDI) of ∑BPs through dust ingestion was the highest in Greece (1.6-17 ng/kg bw/day), Japan (1.3-16) and the U.S. (0.89-9.6) for various age groups. Nevertheless, in comparison with the reported BPA exposure doses through diet, dust ingestion accounted for less than 10% of the total exposure doses in China and the U.S. For TBBPA, the EDI for infants and toddlers ranged from 0.01 to 3.4 ng/kg bw/day, and dust ingestion is an important pathway for exposure accounting for 3.8-35% (median) of exposure doses in China.
Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and microenvironments) dust samples collected from 12 countries (China, Colombia, Greece, India, Japan, Kuwait, Pakistan, Romania, Saudi Arabia, South Korea, U.S., and Vietnam). The concentrations of TBBPA and sum of eight bisphenols (ƩBPs) in dust samples ranged from <1 to 3600 and from 13 to 110,000 ng/g, respectively. The highest TBBPA concentrations in house dust were found in samples from Japan (median: 140 ng/g), followed by South Korea (84 ng/g) and China (23 ng/g). The highest ∑BPs concentrations were found in Greece (median: 3900 ng/g), Japan (2600 ng/g) and the U.S. (2200 ng/g). Significant variations in BPA concentrations were found in dust samples collected from various microenvironments in offices and homes. Concentrations of TBBPA in house dust were significantly correlated with BPA and ∑BPs. Among the nine target chemicals analyzed, BPA was the predominant compound in dust from all countries. The proportion of TBBPA in sum concentrations of nine phenolic compounds analyzed in this study was the highest in dust samples from China (27%) and the lowest in Greece (0.41%). The median estimated daily intake (EDI) of ∑BPs through dust ingestion was the highest in Greece (1.6-17 ng/kg bw/day), Japan (1.3-16) and the U.S. (0.89-9.6) for various age groups. Nevertheless, in comparison with the reported BPA exposure doses through diet, dust ingestion accounted for less than 10% of the total exposure doses in China and the U.S. For TBBPA, the EDI for infants and toddlers ranged from 0.01 to 3.4 ng/kg bw/day, and dust ingestion is an important pathway for exposure accounting for 3.8-35% (median) of exposure doses in China.
Author Gevao, Bondi
Covaci, Adrian
Wang, Wei
Minh, Tu Binh
Malarvannan, Govindan
Kumosani, Taha A.
Moon, Hyo-Bang
Nakata, Haruhiko
Johnson-Restrepo, Boris
Abualnaja, Khalid O.
Asimakopoulos, Alexandros G.
Sinha, Ravindra K.
Kannan, Kurunthachalam
Author_xml – sequence: 1
  givenname: Wei
  surname: Wang
  fullname: Wang, Wei
  organization: Wadsworth Center, New York State Department of Health, Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY 12201-0509, United States
– sequence: 2
  givenname: Khalid O.
  surname: Abualnaja
  fullname: Abualnaja, Khalid O.
  organization: Biochemistry Department, Faculty of Science, Experimental Biochemistry Unit, King Fahd Medical Research Center, Bioactive Natural Products Research Group, King Abdulaziz University, Jeddah, Saudi Arabia
– sequence: 3
  givenname: Alexandros G.
  surname: Asimakopoulos
  fullname: Asimakopoulos, Alexandros G.
  organization: Wadsworth Center, New York State Department of Health, Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY 12201-0509, United States
– sequence: 4
  givenname: Adrian
  surname: Covaci
  fullname: Covaci, Adrian
  organization: Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk-Antwerp, Belgium
– sequence: 5
  givenname: Bondi
  surname: Gevao
  fullname: Gevao, Bondi
  organization: Environmental Management Program, Environment and Life Sciences Center, Kuwait Institute for Scientific Research, P.O. Box 24885, Safat, 13109, Kuwait
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  givenname: Boris
  surname: Johnson-Restrepo
  fullname: Johnson-Restrepo, Boris
  organization: Environmental and Chemistry Group, Sede San Pablo, University of Cartagena, Cartagena, Bolívar 130015, Colombia
– sequence: 7
  givenname: Taha A.
  surname: Kumosani
  fullname: Kumosani, Taha A.
  organization: Biochemistry Department, Faculty of Science, Experimental Biochemistry Unit, King Fahd Medical Research Center, Bioactive Natural Products Research Group, King Abdulaziz University, Jeddah, Saudi Arabia
– sequence: 8
  givenname: Govindan
  surname: Malarvannan
  fullname: Malarvannan, Govindan
  organization: Toxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk-Antwerp, Belgium
– sequence: 9
  givenname: Tu Binh
  surname: Minh
  fullname: Minh, Tu Binh
  organization: Faculty of Chemistry, Hanoi University of Science, Vietnam National University, Hanoi, 19 Le Thanh Tong, Hoan Kiem, Hanoi, Viet Nam
– sequence: 10
  givenname: Hyo-Bang
  surname: Moon
  fullname: Moon, Hyo-Bang
  organization: Department of Marine Sciences and Convergent Technology, College of Science and Technology, Hanyang University, Ansan, South Korea
– sequence: 11
  givenname: Haruhiko
  surname: Nakata
  fullname: Nakata, Haruhiko
  organization: Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555, Japan
– sequence: 12
  givenname: Ravindra K.
  surname: Sinha
  fullname: Sinha, Ravindra K.
  organization: Department of Zoology, Patna University, Patna 800 005, India
– sequence: 13
  givenname: Kurunthachalam
  surname: Kannan
  fullname: Kannan, Kurunthachalam
  email: Kurunthachalam.kannan@health.ny.gov
  organization: Wadsworth Center, New York State Department of Health, Department of Environmental Health Sciences, School of Public Health, State University of New York at Albany, Empire State Plaza, P.O. Box 509, Albany, NY 12201-0509, United States
BackLink https://www.ncbi.nlm.nih.gov/pubmed/26177148$$D View this record in MEDLINE/PubMed
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Human exposure
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SSID ssj0002485
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Snippet Tetrabromobisphenol A (TBBPA) and eight bisphenol analogues (BPs) including bisphenol A (BPA) were determined in 388 indoor (including homes and...
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StartPage 183
SubjectTerms Adolescent
Adult
Aged
Aged, 80 and over
Air Pollutants - analysis
Air Pollution, Indoor - analysis
average daily intake
Benzhydryl Compounds - analysis
Bisphenol A
Bisphenols
BPA
Child
Child, Preschool
China
Colombia
diet
Dust
Dust - analysis
Dust control
Environmental Exposure
Environmental Monitoring
Environmental Pollutants - analysis
Exposure
exposure pathways
Greece
Houses
Human exposure
Humans
India
Indoor dust
Infant
Infant, Newborn
infants
Ingestion
Japan
Kuwait
Microenvironment
Middle Aged
Pakistan
Phenols - analysis
Polybrominated Biphenyls - analysis
Romania
Saudi Arabia
South Korea
TBBPA
toddlers
United States
Vietnam
Young Adult
Title A comparative assessment of human exposure to tetrabromobisphenol A and eight bisphenols including bisphenol A via indoor dust ingestion in twelve countries
URI https://dx.doi.org/10.1016/j.envint.2015.06.015
https://www.ncbi.nlm.nih.gov/pubmed/26177148
https://www.proquest.com/docview/1705733893
https://www.proquest.com/docview/1712771279
https://www.proquest.com/docview/1730069401
https://www.proquest.com/docview/2000327599
Volume 83
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