Study on the Effectiveness of Cardiopulmonary Resuscitation in Elderly Patients Presenting with Cardiopulmonary Arrest on Arrival

Objective This study was conducted to determine whether a policy of not attempting to resuscitate patients who are 80 years of age and older with cardiopulmonary arrest on arrival is justifiable. Methods The protocol of this study was approved without the need for informed consent by the research et...

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Published inInternal Medicine Vol. 54; no. 15; pp. 1859 - 1863
Main Authors Hagiwara, Shuichi, Kaneko, Minoru, Murata, Masato, Aoki, Makoto, Nakajima, Jun, Kanbe, Masahiko, Ohyama, Yoshio, Tamura, Jun'ichi, Oshima, Kiyohiro
Format Journal Article
LanguageEnglish
Published Japan The Japanese Society of Internal Medicine 01.01.2015
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Abstract Objective This study was conducted to determine whether a policy of not attempting to resuscitate patients who are 80 years of age and older with cardiopulmonary arrest on arrival is justifiable. Methods The protocol of this study was approved without the need for informed consent by the research ethics board of Gunma University Hospital. We prospectively analyzed patients with cardiopulmonary arrest on arrival that was due to an intrinsic reason who were taken to Gunma University Hospital between January 2013 and March 2014. The patients were divided into two groups: patients who were less than 80 years of age (L group) and those aged 80 years and older (H group). We compared the patients' characteristics, including the etiology of cardiac arrest, and the prognosis between the two groups. Results A total of 103 patients with cardiopulmonary arrest on arrival were enrolled. There were no significant differences in the patients' characteristics, such as age, sex, witness and bystander cardiopulmonary resuscitation, and transportation time between the two groups. The return of spontaneous circulation was obtained in 14 patients (25.5%) in the L group and in 9 patients (18.8%) in the H group; however, no significant difference was seen between the two groups. Two patients in the L group were in good neurological condition when they were discharged; however, the other patients did not survive. Conclusion Even patients 80 years of age and older can be resuscitated to spontaneous circulation. We do not endorse a policy that recommends not performing cardiopulmonary resuscitation based solely on the age of the patient.
AbstractList This study was conducted to determine whether a policy of not attempting to resuscitate patients who are 80 years of age and older with cardiopulmonary arrest on arrival is justifiable. The protocol of this study was approved without the need for informed consent by the research ethics board of Gunma University Hospital. We prospectively analyzed patients with cardiopulmonary arrest on arrival that was due to an intrinsic reason who were taken to Gunma University Hospital between January 2013 and March 2014. The patients were divided into two groups: patients who were less than 80 years of age (L group) and those aged 80 years and older (H group). We compared the patients' characteristics, including the etiology of cardiac arrest, and the prognosis between the two groups. A total of 103 patients with cardiopulmonary arrest on arrival were enrolled. There were no significant differences in the patients' characteristics, such as age, sex, witness and bystander cardiopulmonary resuscitation, and transportation time between the two groups. The return of spontaneous circulation was obtained in 14 patients (25.5%) in the L group and in 9 patients (18.8%) in the H group; however, no significant difference was seen between the two groups. Two patients in the L group were in good neurological condition when they were discharged; however, the other patients did not survive. Even patients 80 years of age and older can be resuscitated to spontaneous circulation. We do not endorse a policy that recommends not performing cardiopulmonary resuscitation based solely on the age of the patient.
This study was conducted to determine whether a policy of not attempting to resuscitate patients who are 80 years of age and older with cardiopulmonary arrest on arrival is justifiable.OBJECTIVEThis study was conducted to determine whether a policy of not attempting to resuscitate patients who are 80 years of age and older with cardiopulmonary arrest on arrival is justifiable.The protocol of this study was approved without the need for informed consent by the research ethics board of Gunma University Hospital. We prospectively analyzed patients with cardiopulmonary arrest on arrival that was due to an intrinsic reason who were taken to Gunma University Hospital between January 2013 and March 2014. The patients were divided into two groups: patients who were less than 80 years of age (L group) and those aged 80 years and older (H group). We compared the patients' characteristics, including the etiology of cardiac arrest, and the prognosis between the two groups.METHODSThe protocol of this study was approved without the need for informed consent by the research ethics board of Gunma University Hospital. We prospectively analyzed patients with cardiopulmonary arrest on arrival that was due to an intrinsic reason who were taken to Gunma University Hospital between January 2013 and March 2014. The patients were divided into two groups: patients who were less than 80 years of age (L group) and those aged 80 years and older (H group). We compared the patients' characteristics, including the etiology of cardiac arrest, and the prognosis between the two groups.A total of 103 patients with cardiopulmonary arrest on arrival were enrolled. There were no significant differences in the patients' characteristics, such as age, sex, witness and bystander cardiopulmonary resuscitation, and transportation time between the two groups. The return of spontaneous circulation was obtained in 14 patients (25.5%) in the L group and in 9 patients (18.8%) in the H group; however, no significant difference was seen between the two groups. Two patients in the L group were in good neurological condition when they were discharged; however, the other patients did not survive.RESULTSA total of 103 patients with cardiopulmonary arrest on arrival were enrolled. There were no significant differences in the patients' characteristics, such as age, sex, witness and bystander cardiopulmonary resuscitation, and transportation time between the two groups. The return of spontaneous circulation was obtained in 14 patients (25.5%) in the L group and in 9 patients (18.8%) in the H group; however, no significant difference was seen between the two groups. Two patients in the L group were in good neurological condition when they were discharged; however, the other patients did not survive.Even patients 80 years of age and older can be resuscitated to spontaneous circulation. We do not endorse a policy that recommends not performing cardiopulmonary resuscitation based solely on the age of the patient.CONCLUSIONEven patients 80 years of age and older can be resuscitated to spontaneous circulation. We do not endorse a policy that recommends not performing cardiopulmonary resuscitation based solely on the age of the patient.
Objective This study was conducted to determine whether a policy of not attempting to resuscitate patients who are 80 years of age and older with cardiopulmonary arrest on arrival is justifiable. Methods The protocol of this study was approved without the need for informed consent by the research ethics board of Gunma University Hospital. We prospectively analyzed patients with cardiopulmonary arrest on arrival that was due to an intrinsic reason who were taken to Gunma University Hospital between January 2013 and March 2014. The patients were divided into two groups: patients who were less than 80 years of age (L group) and those aged 80 years and older (H group). We compared the patients' characteristics, including the etiology of cardiac arrest, and the prognosis between the two groups. Results A total of 103 patients with cardiopulmonary arrest on arrival were enrolled. There were no significant differences in the patients' characteristics, such as age, sex, witness and bystander cardiopulmonary resuscitation, and transportation time between the two groups. The return of spontaneous circulation was obtained in 14 patients (25.5%) in the L group and in 9 patients (18.8%) in the H group; however, no significant difference was seen between the two groups. Two patients in the L group were in good neurological condition when they were discharged; however, the other patients did not survive. Conclusion Even patients 80 years of age and older can be resuscitated to spontaneous circulation. We do not endorse a policy that recommends not performing cardiopulmonary resuscitation based solely on the age of the patient.
Author Ohyama, Yoshio
Aoki, Makoto
Nakajima, Jun
Kanbe, Masahiko
Hagiwara, Shuichi
Murata, Masato
Tamura, Jun'ichi
Kaneko, Minoru
Oshima, Kiyohiro
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Cites_doi 10.5761/atcs.oa.12.01942
10.1016/j.resuscitation.2014.07.017
10.1097/00003246-199811000-00019
10.1002/ams2.22
10.1136/adc.87.6.526
10.1002/ams2.44
10.1056/NEJM197710132971507
10.1111/j.1532-5415.2011.03400.x
10.1016/j.resuscitation.2013.10.033
10.1186/1865-1380-5-41
10.1038/bmt.2012.244
10.1097/CCM.0b013e31829eb937
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14. Kitamura T, Morita S, Kiyohara K, et al. Trends in survival among elderly patients with out-of-hospital cardiac arrest: a prospective, population-based observation from 1999 to 2011 in Osaka. Resuscitation 85: 1432-1438, 2014.
3. Hagiwara S, Oshima K, Furukawa K, et al. The significance of albumin corrected anion gap in patients with cardiopulmonary Arrest. Ann Thorac Cardiovasc Surg 19: 283-288, 2013.
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6. Hatherill M, Waggie Z, Purves L, et al. Correction of the anion gap for albumin in order to detect occult tissue anions in shock. Arch Dis Child 87: 526-529, 2002.
4. Hagiwara S, Murata M, Kaneko M, et al. Usefulness of serum fibrin degradation products and D-dimer levels as biomarkers to predict return of spontaneous circulation in patients with cardiopulmonary arrest on arrival: comparison with acid-base balance. Acute Med Surg 1: 222-227, 2014.
11. Menon PR, Ehlenbach WJ, Ford DW, et al. Multiple in-hospital resuscitation efforts in elderly. Crit Care Med 42: 108-117, 2014.
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10. Akahane M, Tanabe S, Koike S, et al. Elderly out-of-hospital cardiac arrest has worse outcome with a family bystander than a non-family bystander. Int J Emerg Med 5: 41, 2012.
9. Mohler MJ, Wendel CS, Mosier J, et al. Cardiocerebral resuscitation improves out-of-hospital survival in older adults. JAGS 59: 822-826, 2011.
8. Kanda Y. Investigation of the freely-available easy-to-use software "EZR" (Easy R) for medical statistics. Bone Marrow Transplant 48: 452-458, 2013.
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11
12
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14
1
2
3
4
5
6
7
8
9
10
References_xml – reference: 7. Figge J, Jabor A, Kazda A, Fencl V. Anion gap and hypoalbuminemia. Crit Care Med 26: 1807-1810, 1998.
– reference: 1. Statistics Bureau, Director-General for Policy Planning (Statistical Standards) & Statistical Research and Training Institute of the Ministry of Internal Affairs and Communications, Japan. Statistical Compendia, Historical Statistics of Japan [Internet]. [cited 2014 Nov 1]. Available from: http://www.stat.go.jp/english/data/chouki/index.htm
– reference: 11. Menon PR, Ehlenbach WJ, Ford DW, et al. Multiple in-hospital resuscitation efforts in elderly. Crit Care Med 42: 108-117, 2014.
– reference: 6. Hatherill M, Waggie Z, Purves L, et al. Correction of the anion gap for albumin in order to detect occult tissue anions in shock. Arch Dis Child 87: 526-529, 2002.
– reference: 13. Ishihara K, Hagiwara S, Aoki M, et al. Prognostic factors in emergency patients aged 90 years and older. Acute Med Surg 1: 83-87, 2014.
– reference: 8. Kanda Y. Investigation of the freely-available easy-to-use software "EZR" (Easy R) for medical statistics. Bone Marrow Transplant 48: 452-458, 2013.
– reference: 10. Akahane M, Tanabe S, Koike S, et al. Elderly out-of-hospital cardiac arrest has worse outcome with a family bystander than a non-family bystander. Int J Emerg Med 5: 41, 2012.
– reference: 5. Oh MS, Carroll HJ. Current concepts: the anion gap. N Engl J Med 297: 814-817, 1977.
– reference: 2. Fire and Disaster Management Agency in Japan. Annual report in 2012; 2013 [Internet]. [cited 2014 Nov 1] Available from: http://www.fdma.go.jp/neuter/topics/houdou/h26/2603/260328_1houdou/02_houdoushiryou.pdf (in Japanese).
– reference: 12. Søholm H, Bro-Jeppesen J, Lippert FK, et al. Resuscitaion of patients suffering from sudden cardiac arrest in nursing homes is not futile. Resuscitation 85: 369-375, 2014.
– reference: 9. Mohler MJ, Wendel CS, Mosier J, et al. Cardiocerebral resuscitation improves out-of-hospital survival in older adults. JAGS 59: 822-826, 2011.
– reference: 4. Hagiwara S, Murata M, Kaneko M, et al. Usefulness of serum fibrin degradation products and D-dimer levels as biomarkers to predict return of spontaneous circulation in patients with cardiopulmonary arrest on arrival: comparison with acid-base balance. Acute Med Surg 1: 222-227, 2014.
– reference: 3. Hagiwara S, Oshima K, Furukawa K, et al. The significance of albumin corrected anion gap in patients with cardiopulmonary Arrest. Ann Thorac Cardiovasc Surg 19: 283-288, 2013.
– reference: 14. Kitamura T, Morita S, Kiyohara K, et al. Trends in survival among elderly patients with out-of-hospital cardiac arrest: a prospective, population-based observation from 1999 to 2011 in Osaka. Resuscitation 85: 1432-1438, 2014.
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  doi: 10.5761/atcs.oa.12.01942
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  doi: 10.1016/j.resuscitation.2014.07.017
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  doi: 10.1097/00003246-199811000-00019
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  doi: 10.1002/ams2.22
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  doi: 10.1136/adc.87.6.526
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  doi: 10.1002/ams2.44
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  doi: 10.1056/NEJM197710132971507
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  doi: 10.1111/j.1532-5415.2011.03400.x
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  doi: 10.1016/j.resuscitation.2013.10.033
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  doi: 10.1186/1865-1380-5-41
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  doi: 10.1038/bmt.2012.244
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Snippet Objective This study was conducted to determine whether a policy of not attempting to resuscitate patients who are 80 years of age and older with...
This study was conducted to determine whether a policy of not attempting to resuscitate patients who are 80 years of age and older with cardiopulmonary arrest...
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SubjectTerms advanced life support
Age Factors
Aged
Aged, 80 and over
cardiopulmonary arrest on arrival
cardiopulmonary resuscitation
Cardiopulmonary Resuscitation - methods
Cardiopulmonary Resuscitation - utilization
Clinical Protocols
elderly
Female
Heart Arrest - mortality
Heart Arrest - therapy
Hospitals, University - statistics & numerical data
Humans
Male
out-of-hospital cardiac arrest
Policy Making
Prognosis
Survival Rate
Title Study on the Effectiveness of Cardiopulmonary Resuscitation in Elderly Patients Presenting with Cardiopulmonary Arrest on Arrival
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