Species-specific emergence of H7 highly pathogenic avian influenza virus is driven by intrahost selection differences between chickens and ducks

• Published in: PLoS pathogens Vol. 20; no. 2; p. e1011942
• Main Authors: de Bruin, Anja C. M., Spronken, Monique I., Kok, Adinda, Rosu, Miruna E., de Meulder, Dennis, van Nieuwkoop, Stefan, Lexmond, Pascal, Funk, Mathis, Leijten, Lonneke M., Bestebroer, Theo M., Herfst, Sander, van Riel, Debby, Fouchier, Ron A. M., Richard, Mathilde
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.02.2024; Public Library of Science (PLoS)
• Subjects: Animals; Animals, Wild; Aquatic birds; Avian flu; Biology and Life Sciences; Chickens; Drinking water; Ducks; Ecology and Environmental Sciences; Epitopes; Fibroblasts; Flow cytometry; Hemagglutinins; Hemorrhagic disease; Humans; Hypotheses; Infections; Influenza; Influenza A virus - genetics; Influenza A Virus, H7N7 Subtype; Influenza in Birds; Medicine and Health Sciences; Orthomyxoviridae; Peptides; Poultry; Poultry Diseases; Proteins; Replication; Systemic diseases; Tropism; Viruses; Waterfowl; Wildfowl; Netherlands

Highly pathogenic avian influenza viruses (HPAIVs) cause severe hemorrhagic disease in terrestrial poultry and are a threat to the poultry industry, wild life, and human health. HPAIVs arise from low pathogenic avian influenza viruses (LPAIVs), which circulate in wild aquatic birds. HPAIV emergence...