Preclinical models of diabetic wound healing: A critical review

• Published in: Biomedicine & pharmacotherapy Vol. 142; p. 111946
• Main Authors: Sanapalli, Bharat Kumar Reddy, Yele, Vidyasrilekha, Singh, Mantosh Kumar, Thaggikuppe Krishnamurthy, Praveen, Karri, Veera Venkata Satyanarayana Reddy
• Format: Journal Article
• Language: English
• Published: France Elsevier Masson SAS 01.10.2021
• Subjects: Animal models; Animals; Diabetes Complications - metabolism; Diabetes Mellitus - metabolism; Diabetic induction; Diabetic wound; Disease Models, Animal; Humans; Mammals; Rodentia; Translational Research, Biomedical - methods; Wound Healing - physiology; Diabetic induction; Diabetic wound; Animal models

The treatment of diabetic wounds (DWs) is always challenging for the medical community because of its multifaceted pathophysiology. Due to practical and ethical considerations, direct studies of therapeutic interventions on human subjects are limited. Thus, it is ideal for performing studies on anim...