Species-specific IL-1β is an inflammatory sensor of Seneca Valley Virus 3C Protease - Huang, Xiangyu; Zhao, Zhenchao; Zhu, Cheng; Chai, Lvye; Yan, Ya; Yuan, Ye; Wu, Lei; Li, Minjie; Jiang, Xiaohan; Wang, Haiwei; Liu, Zheng; Li, Pingwei; et al. (PLoS pathogens, 2024)
Keywords: 3C Viral Proteases - metabolism; Alveoli; Animals; Biology and Life Sciences; Caspase-1; Caspase-4; Cell culture; Cell death; Chromatography; Cleavage; Cysteine Endopeptidases - metabolism; Enzymes; Humans; Hydrophobicity; IL-1β; Infections; Inflammasomes; Inflammasomes - metabolism; Inflammation; Inflammation - metabolism; Interleukin 18; Interleukin-1beta - metabolism; Macrophages; Macrophages, Alveolar - metabolism; Macrophages, Alveolar - virology; Medicine and Health Sciences; Molecular modelling; Morphology; Mutagenesis; Picornaviridae; Picornaviridae Infections - metabolism; Picornaviridae Infections - virology; Plasmids; Protease; Proteinase; Research and Analysis Methods; Species Specificity; Substrates; Swine; Viral infections; Viral Proteins - metabolism; Viruses