Safety and tolerability of transition from inhaled treprostinil to oral selexipag in pulmonary arterial hypertension: Results from the TRANSIT-1 study - Frost, Adaani; Janmohamed, Munir; Fritz, Jason S.; McConnell, John W.; Poch, David; Fortin, Terry Ann; Miller, Chad E.; Chin, Kelly M.; Fisher, Micah; Eggert, Michael; McEvoy, Colleen; Benza, Raymond L.; et al. (The Journal of heart and lung transplantation, 2019)
Keywords: Acetamides - administration & dosage; Administration, Inhalation; Administration, Oral; Antihypertensive Agents - administration & dosage; Dose-Response Relationship, Drug; Drug Substitution; Drug Tolerance; Epoprostenol - administration & dosage; Epoprostenol - analogs & derivatives; Female; Follow-Up Studies; Humans; inhaled treprostinil; Male; Middle Aged; Prodrugs; Prospective Studies; prostacyclin-pathway targeting therapy; pulmonary arterial hypertension; Pulmonary Arterial Hypertension - drug therapy; Pulmonary Arterial Hypertension - physiopathology; Pulmonary Wedge Pressure - physiology; Pyrazines - administration & dosage; selexipag; Treatment Outcome; treatment transition; selexipag; inhaled treprostinil; prostacyclin-pathway targeting therapy; pulmonary arterial hypertension; treatment transition