Genetic Mapping of the HLA1 Locus Causing Hybrid Lethality in Nicotiana Interspecific Hybrids

• Published in: Plants (Basel) Vol. 10; no. 10; p. 2062
• Main Authors: Tezuka, Takahiro, Kitamura, Naoto, Imagawa, Sae, Hasegawa, Akira, Shiragaki, Kumpei, He, Hai, Yanase, Masanori, Ogata, Yoshiyuki, Morikawa, Toshinobu, Yokoi, Shuji
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 30.09.2021; MDPI
• Subjects: Alleles; Amplification; Amplified fragment length polymorphism; Apoptosis; Binding sites; Chromosomes; Deoxyribonucleic acid; Disease resistance; DNA; Epistasis; Gene mapping; Genes; Genomes; Histocompatibility antigen HLA; Homology; hybrid lethality; Hybrids; Interspecific hybridization; interspecific population; Lethality; Linkage analysis; Loci; Markers; Nicotiana; Nicotiana debneyi; Nicotiana fragrans; Nucleotide sequence; Polymerase chain reaction; Polymorphism; Population genetics; Random amplified polymorphic DNA; Reproductive isolation; Seedlings; Seeds

Hybrid lethality, a postzygotic mechanism of reproductive isolation, is a phenomenon that causes the death of F1 hybrid seedlings. Hybrid lethality is generally caused by the epistatic interaction of two or more loci. In the genus Nicotiana, N. debneyi has the dominant allele Hla1-1 at the HLA1 locu...