Morphology and natural history of familial adenomatous polyposis-associated dysplastic fundic gland polyps

• Published in: Histopathology Vol. 65; no. 3; pp. 353 - 362
• Main Authors: Arnason, Thomas, Liang, Wen-Yih, Alfaro, Eduardo, Kelly, Paul, Chung, Daniel C, Odze, Robert D, Lauwers, Gregory Y
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.09.2014; Wiley Subscription Services, Inc
• Subjects: Adenomatous Polyposis Coli - etiology; Adenomatous Polyposis Coli - pathology; Adenomatous Polyps - etiology; Adenomatous Polyps - pathology; Adolescent; Adult; Aged; Aged, 80 and over; Cohort Studies; Disease Progression; dysplasia; familial adenomatous polyposis; Female; fundic gland polyp; Gastric Fundus - pathology; Gastric Mucosa - pathology; Humans; Male; Middle Aged; Retrospective Studies; Risk Factors; stomach; Stomach Neoplasms - etiology; Stomach Neoplasms - pathology; Young Adult; dysplasia; fundic gland polyp; stomach; familial adenomatous polyposis

Aims Most patients with familial adenomatous polyposis (FAP) develop gastric fundic gland polyps, with many displaying low‐grade dysplasia. This study evaluates the natural history and morphological phenotype of dysplasia in FAP‐associated fundic gland polyps. Methods and results Patients with FAP a...