Relationship of Liver X Receptors α and Endoglin Levels in Serum and Placenta with Preeclampsia

• Published in: PloS one Vol. 11; no. 10; p. e0163742
• Main Authors: Wang, Jing, Dong, Xing, Wu, Hong-yan, Wu, Nan, Zhang, Xue-jun, Wang, Xin, Shang, Li-xin
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 13.10.2016; Public Library of Science (PLoS)
• Subjects: Adult; Biology and Life Sciences; Cholesterol; Colorectal cancer; Correlation analysis; Endoglin; Endoglin - analysis; Endoglin - blood; Endoglin - genetics; Enzyme-linked immunosorbent assay; Female; Gene Expression Regulation; Gynecology; Humans; Immunohistochemistry; Liver; Liver X receptors; Liver X Receptors - analysis; Liver X Receptors - blood; Liver X Receptors - genetics; Medicine and Health Sciences; Metabolism; Obstetrics; Pathogenesis; Patients; Placenta; Placenta - metabolism; Placenta - pathology; Pre-eclampsia; Pre-Eclampsia - blood; Pre-Eclampsia - diagnosis; Pre-Eclampsia - genetics; Pre-Eclampsia - pathology; Predictions; Preeclampsia; Pregnancy; Receptors; Research and Analysis Methods; Substance abuse treatment; Young Adult; Beijing China; China

Liver X receptor alpha (LXRα) and endoglin have been postulated to play roles in trophoblast invasion and lipid metabolic disturbances. However, the relationship between LXRα and endoglin levels in serum and placenta of patients with preeclampsia remains poorly understood. The objective of this stud...