Calculating air volume fractions from computed tomography images for chronic obstructive pulmonary disease diagnosis

• Published in: PloS one Vol. 15; no. 4; p. e0231730
• Main Authors: Chuang, Chun-Chao, Chou, Ying-Hsiang, Peng, Shin-Lei, Tai, Jou-Erh, Lee, Shan-Chih, Tyan, Yeu-Sheng, Shih, Cheng-Ting
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 16.04.2020; Public Library of Science (PLoS)
• Subjects: Air Content; Attenuation; Biology and Life Sciences; Biomarkers; Chronic obstructive pulmonary disease; Computed tomography; Diagnosis; Emphysema; Foams; Histograms; Hospitals; Image processing; Image segmentation; Lung diseases; Lungs; Medical diagnosis; Medical imaging; Medicine and Health Sciences; Methods; Mortality; Obstructive lung disease; Patients; Physical Sciences; Research and Analysis Methods; Thickness; Tomography; Taiwan

Quantitative evaluation using image biomarkers calculated from threshold-segmented low-attenuation areas on chest computed tomography (CT) images for diagnosing chronic obstructive pulmonary diseases (COPD) has been widely investigated. However, the segmentation results depend on the applied thresho...