Delta Inulin Adjuvant Enhances Plasmablast Generation, Expression of Activation-Induced Cytidine Deaminase and B-Cell Affinity Maturation in Human Subjects Receiving Seasonal Influenza Vaccine - Li, Lei; Honda-Okubo, Yoshikazu; Li, Connie; Sajkov, Dimitar; Petrovsky, Nikolai (PloS one, 2015)
Keywords: Activation-induced cytidine deaminase; Adjuvants; Adult; Affinity; Aged; Aged, 80 and over; Animal models; Antibody Affinity - drug effects; Antibody Affinity - immunology; Antibody Formation - drug effects; Antigens; Avidity; B-cell receptor; Clinical trials; Combined vaccines; Complementarity Determining Regions - genetics; Complementarity Determining Regions - immunology; Complementarity-determining region 3; Cryopreservation; Cytidine deaminase; Cytidine Deaminase - metabolism; Deoxyribonucleic acid; DNA; Encephalitis; Female; Gene expression; Hepatitis; Human behavior; Humans; Immunity; Immunization; Immunogenicity; Immunoglobulin G - immunology; Immunoglobulins; Influenza; Influenza Vaccines - administration & dosage; Influenza Vaccines - immunology; Influenza Vaccines - pharmacology; Inulin; Inulin - administration & dosage; Inulin - analogs & derivatives; Inulin - pharmacology; Lymphocytes; Lymphocytes B; Male; Maturation; Medical research; Middle Aged; Mutagenesis; Mutation; Mutation - genetics; Pandemics; Peripheral blood; Plasma Cells - drug effects; Plasma Cells - immunology; Receptors, Antigen, B-Cell - metabolism; Seasons; T cell receptors; Vaccination; Vaccines; Viruses; Young Adult