The Effect of Peritoneal Fluid from Patients with Endometriosis on Mitochondrial Function and Development of Early Mouse Embryos

• Published in: PloS one Vol. 8; no. 12; p. e82334
• Main Authors: Shu, Jing, Xing, Lili, Ding, Guolian, Luo, Qiong, Liu, Xinmei, Yan, Qingfeng, Sheng, Jianzhong, Huang, Hefeng
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 26.12.2013; Public Library of Science (PLoS)
• Subjects: Adenosine triphosphate; Adenosine Triphosphate - metabolism; Adult; Animals; Ascitic Fluid - metabolism; ATP; Cleavage; Deoxyribonucleic acid; Developmental stages; DNA; DNA, Mitochondrial - drug effects; Eggs; Embryonic Development - drug effects; Embryos; Endocrinology; Endometriosis; Female; Fluids; Free radicals; Gynecology; Humans; Infertility; Laparoscopy; Medicine; Membrane potential; Membrane Potential, Mitochondrial - drug effects; Menstruation; Mice; Mitochondria; Mitochondria - drug effects; Mitochondria - ultrastructure; Mitochondrial DNA; Nitric oxide; Nitric Oxide - metabolism; Obstetrics; Oxidative stress; Patients; Peritoneal fluid; Peritoneum; Signal transduction; Sperm; Studies; Womens health; China

Peritoneal fluid (PF) from patients with endometriosis can inhibit early embryo development via probable functional changes of embryo mitochondria in the early stage of embryo development. The purpose of this study was to determine the effect of PF from patients with endometriosis on mitochondrial f...