ICln: A New Regulator of Non-Erythroid 4.1R Localisation and Function

• Published in: PloS one Vol. 9; no. 10; p. e108826
• Main Authors: Bazzini, Claudia, Benedetti, Lorena, Civello, Davide, Zanoni, Chiara, Rossetti, Valeria, Marchesi, Davide, Garavaglia, Maria Lisa, Paulmichl, Markus, Francolini, Maura, Meyer, Giuliano, Rodighiero, Simona
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.10.2014; Public Library of Science (PLoS)
• Subjects: Actin; Amino acids; Biology and Life Sciences; Cell Line; Cell morphology; Cell size; Cytology; Cytoplasm; Cytoskeletal Proteins - metabolism; Cytoskeleton; Cytoskeleton - metabolism; Dislocations; ELAV Proteins - metabolism; ELAV-Like Protein 2; HEK293 Cells; Humans; Isoforms; Kinases; Localization; Machinery and equipment; Membrane Proteins - metabolism; Overexpression; Protein Binding; Protein interaction; Protein Isoforms - metabolism; Proteins; Research and Analysis Methods; Ribonucleic acid; RNA; RNA processing; Rodents; Splicing; Italy

To optimise the efficiency of cell machinery, cells can use the same protein (often called a hub protein) to participate in different cell functions by simply changing its target molecules. There are large data sets describing protein-protein interactions ("interactome") but they frequentl...