Deformation Effect on SUVmax Changes in Thoracic Tumors Using 4-D PET/CT Scan

• Published in: PloS one Vol. 8; no. 3; p. e58886
• Main Authors: Huang, Tzung-Chi, Wang, Yao-Ching
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 14.03.2013; Public Library of Science (PLoS)
• Subjects: Adult; Cancer; Computed tomography; Deformation effects; Engineering; Esophageal cancer; Esophagus; Female; Four-Dimensional Computed Tomography; Humans; Image acquisition; Image reconstruction; Imaging, Three-Dimensional; Localization; Lung cancer; Lung diseases; Male; Medical imaging; Medicine; Middle Aged; Movement; Multimodal Imaging; Optical flow (image analysis); Patients; Positron emission; Positron-Emission Tomography; Radiation; Radiation therapy; Respiration; Respiratory-Gated Imaging Techniques; Thoracic Neoplasms - diagnostic imaging; Thoracic Neoplasms - physiopathology; Thorax; Tomography; Tomography, X-Ray Computed; Tumors
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0058886

Respiratory motion blurs the standardized uptake value (SUV) and leads to a further signal reduction and changes in the SUV maxima. 4D PET can provide accurate tumor localization as a function of the respiratory phase in PET/CT imaging. We investigated thoracic tumor motion by respiratory 4D CT and...