Genetic Relatedness between Pneumococcal Populations Originating from the Nasopharynx, Adenoid, and Tympanic Cavity of Children with Otitis Media

• Published in: Journal of Clinical Microbiology Vol. 43; no. 7; pp. 3140 - 3144
• Main Authors: Tonnaer, Edith L, Rijkers, Ger T, Meis, Jacques F, Klaassen, Corné H, Bogaert, Debby, Hermans, Peter W, Curfs, Jo H
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.07.2005
• Subjects: Adenoids - microbiology; Bacteriology; Biological and medical sciences; Child; Child, Preschool; Culture Media; DNA, Bacterial - analysis; Ear, Middle - microbiology; Fundamental and applied biological sciences. Psychology; Humans; Infectious diseases; Medical sciences; Microbiology; Miscellaneous; Nasopharynx - microbiology; Otitis Media with Effusion - microbiology; Pneumococcal Infections - microbiology; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Streptococcus pneumoniae - classification; Streptococcus pneumoniae - genetics; Streptococcus pneumoniae - isolation & purification; Human; Streptococcaceae; Microbiology; Middle ear disease; Bacteria; Micrococcales; ENT disease; Otitis media; Child; Population genetics; Streptococcus pneumoniae

Previous studies have shown that Streptococcus pneumoniae exists in both middle ear effusions and the upper respiratory region from children with otitis media with effusion (OME), but it remains unclear whether these strains represent genetically identical clones. Therefore, it cannot be determined...