Atrial Fibrillation Ablation: Indications, Outcomes, Complications, and Future Directions
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia which affects 33 million individuals worldwide? It is associated with many adverse outcomes, including stroke, dementia, heart failure (HF), and mortality. Based on a growing body of evidence illustrating its efficacy and safety,...
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Published in | Chinese medical journal Vol. 130; no. 16; pp. 1891 - 1893 |
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Format | Journal Article |
Language | English |
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China
Medknow Publications and Media Pvt. Ltd
20.08.2017
Lippincott Williams & Wilkins Ovid Technologies Medknow Publications & Media Pvt Ltd Wolters Kluwer |
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Abstract | Atrial fibrillation (AF) is the most common type of cardiac arrhythmia which affects 33 million individuals worldwide? It is associated with many adverse outcomes, including stroke, dementia, heart failure (HF), and mortality. Based on a growing body of evidence illustrating its efficacy and safety, catheter ablation (CA) has become an important treatment strategy for symptomatic AF. Most centers have progressively moved from performing paroxysmal AF to more complex long-standing persistent AF or patients with more comorbidities. |
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AbstractList | Indications and Patient Selection Multiple clinical trials have established the superiority of CA over antiarrhythmic drug therapy (AAD) for the maintenance of sinus rhythm and improvement of quality of life. The European Society of Cardiology (ESC) and the American Heart Association/American College of Cardiology/Heart Rhythm Society guidelines both recommend CA in patients with symptomatic recurrences of AF on AAD therapy (I, A for paroxysmal; IIa, C for persistent). [7] Assessment of CA for appropriate AF patients depends on multiple variables including AF type, left atrial (LA) size, the severity of symptoms, the presence of associated cardiovascular disease, and patient preference. A propensity-matched analysis of medically treated and ablated patients from the US Matket Scan Research Database Data (801 pairs matched) confirmed that CA was associated with a reduced risk of stroke/TIA compared with the control group (hazard ratio [HR]: 0.62, 95% confidential interval [CI]: 0.44-0.86). Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial (NCT00911508) and Early Therapy of Atrial Fibrillation for Stroke Prevention Trial (NCT01288352), will provide new insights and establish whether AF ablation provides a significant reduction in stroke, death, and HF compared with standard management. Safety Improvement Initiative for Atrial Fibrillation Ablation With the rapid development of CA in China, the number of AF ablation performed in China has increasing from 11 cases in 1998 to more than 30,000 cases in 2016. The Chinese Heart Rhythm Society (CHRS) put forward the "AF catheter ablation safety improvement initiative," and put "Restore normal rhythm with doubled safety" as this year's conference... Atrial fibrillation (AF) is the most common type of cardiac arrhythmia which affects 33 million individuals worldwide? It is associated with many adverse outcomes, including stroke, dementia, heart failure (HF), and mortality. Based on a growing body of evidence illustrating its efficacy and safety, catheter ablation (CA) has become an important treatment strategy for symptomatic AF. Most centers have progressively moved from performing paroxysmal AF to more complex long-standing persistent AF or patients with more comorbidities. |
Audience | Academic |
Author | Xue-Yuan Guo Chang-Sheng Ma |
AuthorAffiliation | Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China |
AuthorAffiliation_xml | – name: Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28776538$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1016/j.jacc.2009.02.022 10.1111/j.1540-8167.2011.02010.x 10.1016/S0140-6736(16)31277-6 10.1111/jce.12849 10.1056/NEJMoa1113566 10.1016/j.jacc.2014.03.022 10.1161/CIRCOUTCOMES.111.963108 10.1161/CIRCULATIONAHA.113.005119 10.1093/eurheartj/eht194 10.1016/j.hrthm.2014.09.049 10.1093/eurheartj/ehw087 10.1001/jama.2014.3 10.1016/j.jacc.2009.02.024 10.1016/j.jacc.2012.04.060 10.1093/eurheartj/ehw210 10.1161/CIRCULATIONAHA.115.019406 10.1001/jama.2014.467 10.1016/j.cjca.2013.07.679 10.1161/CIRCULATIONAHA.113.003862 |
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Notes | Atrial fibrillation (AF) is the most common type of cardiac arrhythmia which affects 33 million individuals worldwide? It is associated with many adverse outcomes, including stroke, dementia, heart failure (HF), and mortality. Based on a growing body of evidence illustrating its efficacy and safety, catheter ablation (CA) has become an important treatment strategy for symptomatic AF. Most centers have progressively moved from performing paroxysmal AF to more complex long-standing persistent AF or patients with more comorbidities. 11-2154/R Atrial Fibrillation; Catheter Ablation; Complications; Indications; Ovtcomes SourceType-Other Sources-1 content type line 63 ObjectType-Editorial-2 ObjectType-Commentary-1 |
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Snippet | Atrial fibrillation (AF) is the most common type of cardiac arrhythmia which affects 33 million individuals worldwide? It is associated with many adverse... Indications and Patient Selection Multiple clinical trials have established the superiority of CA over antiarrhythmic drug therapy (AAD) for the maintenance of... |
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StartPage | 1891 |
SubjectTerms | Ablation (Surgery) Atrial fibrillation Atrial Fibrillation; Catheter Ablation; Complications; Indications; Outcomes Cardiac arrhythmia Care and treatment Catheters Complications and side effects Mortality NMR Nuclear magnetic resonance Stroke 不良后果 并发症 心力衰竭 心律失常 心房 死亡率 适应症 颤动 |
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Title | Atrial Fibrillation Ablation: Indications, Outcomes, Complications, and Future Directions |
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