Neuraminidase antigenic drift of H3N2 clade 3c.2a viruses alters virus replication, enzymatic activity and inhibitory antibody binding - Powell, Harrison; Pekosz, Andrew (PLoS pathogens, 2020)
Keywords: Animals; Antibodies; Antibodies, Monoclonal - immunology; Antibodies, Viral - immunology; Antigenic drift; Antigens; Binding; Biology and Life Sciences; Cell differentiation; Dogs; Enzymatic activity; Epithelial cells; Epitopes; Exo-a-sialidase; Genotype & phenotype; Genotypes; Glycan; Glycosylation; HEK293 Cells; Humans; Immunology; Infections; Influenza; Influenza A; Influenza A Virus, H3N2 Subtype - physiology; Influenza, Human - genetics; Influenza, Human - immunology; Madin Darby Canine Kidney Cells; Medicine and Health Sciences; Monoclonal antibodies; Mutation; Neuraminidase - genetics; Neuraminidase - immunology; Neutralization; Proteins; Public health; Rabbits; Replication; Vaccines; Viral Proteins - genetics; Viral Proteins - immunology; Virus Replication - genetics; Virus Replication - immunology; Viruses; United States--US; Maryland; Baltimore Maryland