Cerebrovascular pressure reactivity monitoring using wavelet analysis in traumatic brain injury patients: A retrospective study

• Published in: PLoS medicine Vol. 14; no. 7; p. e1002348
• Main Authors: Liu, Xiuyun, Donnelly, Joseph, Czosnyka, Marek, Aries, Marcel J H, Brady, Ken, Cardim, Danilo, Robba, Chiara, Cabeleira, Manuel, Kim, Dong-Joo, Haubrich, Christina, Hutchinson, Peter J, Smielewski, Peter
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.07.2017; Public Library of Science (PLoS)
• Subjects: Adult; Biology and Life Sciences; Blood; Blood pressure; Blood Pressure Determination - instrumentation; Blood Pressure Determination - methods; Brain; Brain Injuries, Traumatic - diagnosis; Cerebrovascular system; Clinical outcomes; Curve fitting; England; Female; Heart rate; Humans; Injury analysis; Intracranial Pressure; Male; Medicine and Health Sciences; Methods; Middle Aged; Monitoring, Physiologic - methods; Mortality; Neurosciences; Neurosurgery; Patients; People and Places; Perfusion; Physical Sciences; Physiology; Prognosis; Reactivity; Reproducibility of Results; Research and Analysis Methods; Respiration; Retrospective Studies; Software; Standard deviation; Studies; Traumatic brain injury; Variance; Wavelet Analysis; Wavelet transforms; Young Adult

After traumatic brain injury (TBI), the ability of cerebral vessels to appropriately react to changes in arterial blood pressure (pressure reactivity) is impaired, leaving patients vulnerable to cerebral hypo- or hyperperfusion. Although, the traditional pressure reactivity index (PRx) has demonstra...